Famprofazone
Encyclopedia
Famprofazone is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone
series which is available over-the-counter in some countries such as Taiwan
. It has analgesic
, anti-inflammatory
, and antipyretic
effects. Famprofazone has been known to produce methamphetamine
as an active
metabolite
, with 15-20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing false positives on drug test
s for amphetamine
s.
Pyrazolone
Pyrazolone, a five-membered-ring lactam, is a derivative of pyrazole that has an additional keto group.It has a molecular formula of C3H4N2O.Examples of derivatives include:* Ampyrone* Metamizole* Phenazone-External links:* *...
series which is available over-the-counter in some countries such as Taiwan
Taiwan
Taiwan , also known, especially in the past, as Formosa , is the largest island of the same-named island group of East Asia in the western Pacific Ocean and located off the southeastern coast of mainland China. The island forms over 99% of the current territory of the Republic of China following...
. It has analgesic
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
, anti-inflammatory
Anti-inflammatory
Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system....
, and antipyretic
Antipyretic
Antipyretics ; an-tee-pahy-ret-iks; from the Greek anti, against, and pyreticus, are drugs or herbs that reduce fever. Normally, they will not lower body temperature if one does not have a fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature...
effects. Famprofazone has been known to produce methamphetamine
Methamphetamine
Methamphetamine is a psychostimulant of the phenethylamine and amphetamine class of psychoactive drugs...
as an active
Activity (chemistry)
In chemical thermodynamics, activity is a measure of the “effective concentration” of a species in a mixture, meaning that the species' chemical potential depends on the activity of a real solution in the same way that it would depend on concentration for an ideal solution.By convention, activity...
metabolite
Metabolite
Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial...
, with 15-20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing false positives on drug test
Drug test
A drug test is a technical analysis of a biological specimen – for example urine, hair, blood, sweat, or oral fluid / saliva – to determine the presence or absence of specified parent drugs or their metabolites...
s for amphetamine
Substituted amphetamine
Substituted amphetamines are a chemical class of stimulants, entactogens, hallucinogens, and other drugs. They feature a phenethylamine core with a methyl group attached to the alpha carbon resulting in amphetamine, along with additional substitutions...
s.