Erminio Costa
Encyclopedia
Erminio Costa was a neuroscientist
. His research interests covered brain serotonergic activity in health and disease, benzodiazepine
-GABA
interactions, benzodiazepine action at GABAA receptors, and GABAergic dysfunction and changes in the expression of reelin
and GAD67
in schizophrenia
. He published more than 1000 articles.
Neuroscientist
A neuroscientist is an individual who studies the scientific field of neuroscience or any of its related sub-fields...
. His research interests covered brain serotonergic activity in health and disease, benzodiazepine
Benzodiazepine
A benzodiazepine is a psychoactive drug whose core chemical structure is the fusion of a benzene ring and a diazepine ring...
-GABA
Gabâ
Gabâ or gabaa, for the people in many parts of the Philippines), is the concept of a non-human and non-divine, imminent retribution. A sort of negative karma, it is generally seen as an evil effect on a person because of their wrongdoings or transgressions...
interactions, benzodiazepine action at GABAA receptors, and GABAergic dysfunction and changes in the expression of reelin
Reelin
Reelin is a large secreted extracellular matrix protein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates the...
and GAD67
Glutamate decarboxylase
Glutamate decarboxylase or glutamic acid decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor. The reaction proceeds as follows:...
in schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...
. He published more than 1000 articles.
Career
- July, 1947 - M.D. 110/110 cum laude, University of CagliariUniversity of CagliariThe University of Cagliari is a university located in Cagliari, Italy. It was founded in 1620 and is organized in 11 Faculties.-History:The Studium Generalis Kalaritanum was founded in 1606 along the lines of the old Spanish Universities of Salamanca, Valladolid and Lérida...
, Italy - 1950-1960 - Thudichum Psychiatric Research Laboratory, Galesburg Research Hospital, GalesburgGalesburg, IllinoisGalesburg is a city in Knox County, Illinois, in the United States. As of the 2010 census, the city population was 32,195. It is the county seat of Knox County....
, Illinois - 1960-1965 - Deputy Chief, Laboratory of Chemical Pharmacology at NHLI - NIH, Bethesda, Maryland
- 1965-1968 - Associate Professor of Pharmacology and Neurology, College of Physicians and Surgeons of Columbia UniversityColumbia UniversityColumbia University in the City of New York is a private, Ivy League university in Manhattan, New York City. Columbia is the oldest institution of higher learning in the state of New York, the fifth oldest in the United States, and one of the country's nine Colonial Colleges founded before the...
, New York, NY - 1968-1985 - Chief of the Laboratory of Preclinical Pharmacology, NIMH, St. Elizabeths HospitalSt. Elizabeths HospitalSt. Elizabeths Hospital is a psychiatric hospital operated by the District of Columbia Department of Mental Health. It was the first large-scale, federally-run psychiatric hospital in the United States. Housing several thousand patients at its peak, St. Elizabeths had a fully functioning...
, Washington, DC - 1985-1994 - Director and Founder, Institute of Neuroscience, and Professor of Pharmacology, Georgetown UniversityGeorgetown UniversityGeorgetown University is a private, Jesuit, research university whose main campus is in the Georgetown neighborhood of Washington, D.C. Founded in 1789, it is the oldest Catholic university in the United States...
, Washington, DC - 1994-1995 - Director, Center for Neuropharmacology, Nathan Kline Institute for Psychiatric ResearchNathan Kline Institute for Psychiatric ResearchThe Nathan S. Kline Institute for Psychiatric Research is a New York State-funded research Institute, located in Orangeburg, New York.NKI is dedicated to research designed to better understand the causes of mental illnesses, and to improving the lives of people with mental illness. The Institute...
, New York University, New York, NY - 1995 - Scientific Director, Psychiatric Institute, Professor of Biochemistry in Psychiatry, Department of Psychiatry, College of Medicine, University of Illinois at ChicagoUniversity of Illinois at ChicagoThe University of Illinois at Chicago, or UIC, is a state-funded public research university located in Chicago, Illinois, United States. Its campus is in the Near West Side community area, near the Chicago Loop...
, Chicago, Illinois - 1982 - Member, National Academy of SciencesUnited States National Academy of SciencesThe National Academy of Sciences is a corporation in the United States whose members serve pro bono as "advisers to the nation on science, engineering, and medicine." As a national academy, new members of the organization are elected annually by current members, based on their distinguished and...
- 1991 - Member of "Accademia dei LinceiAccademia dei LinceiThe Accademia dei Lincei, , is an Italian science academy, located at the Palazzo Corsini on the Via della Lungara in Rome, Italy....
" founded by Galileo GalileiGalileo GalileiGalileo Galilei , was an Italian physicist, mathematician, astronomer, and philosopher who played a major role in the Scientific Revolution. His achievements include improvements to the telescope and consequent astronomical observations and support for Copernicanism...
in 1602, Rome
Books
- Advances in Biochemical Psychopharmacology (1969)
- Biochemistry and Pharmacology of the Basal Ganglia (1966)
- Biochemistry of Simple Neuronal Models (1970)
- Neurosteroids and Brain Function (1991)
- The Endorphins - Vol. 18 (1985)
See also
- Bernard BrodieBernard Brodie (biochemist)Bernard Beryl Brodie , a leading researcher on drug therapy, is considered by many to be the founder of modern pharmacology and brought the field to prominence in the 1940s and 1950s. He was a major figure in the field of drug metabolism, the study of how drugs interact in the body and how they...
, in whose laboratory Costa worked for a time.
External links
- Erminio Costa, M.D.
- Obituary—Erminio Costa, M.D. (1924-2009), University of Illinois at Chicago - obituary at Schizophrenia Research ForumSchizophrenia Research ForumSchizophrenia Research Forum is a website dedicated to convey information about schizophrenia.It hosts the SzGene Database, which provides a comprehensive, unbiased and regularly updated field synopsis of genetic association studies performed in schizophrenia with hundreds of up-to-date...