Enterogastric reflex
Encyclopedia
The Enterogastric reflex is one of three extrinsic reflexes of the Gastrointestinal Tract
Gastrointestinal tract
The human gastrointestinal tract refers to the stomach and intestine, and sometimes to all the structures from the mouth to the anus. ....

. The reflex is stimulated by the presence of acid levels in the duodenum
Duodenum
The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms anterior intestine or proximal intestine may be used instead of duodenum...

 at a pH of 3-4 or in the stomach at a pH of 1.5. Upon stimulation of the reflex, the release of gastrin
Gastrin
In humans, gastrin is a peptide hormone that stimulates secretion of gastric acid by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the antrum of the stomach, duodenum, and the pancreas...

 from G-cells in the antrum of the stomach
Stomach
The stomach is a muscular, hollow, dilated part of the alimentary canal which functions as an important organ of the digestive tract in some animals, including vertebrates, echinoderms, insects , and molluscs. It is involved in the second phase of digestion, following mastication .The stomach is...

 is shut off. This in turn inhibits gastric motility and secretion of gastric acid
Gastric acid
Gastric acid is a digestive fluid, formed in the stomach. It has a pH of 1 to 2 and is composed of hydrochloric acid , and large quantities of potassium chloride and sodium chloride...

 (HCl
HCL
HCL or HCl can stand for:* Hairy cell leukemia, an uncommon and slowly progressing B cell leukemia* Hardware compatibility list...

). In addition to the Enterogastric reflex, the other two extrinsic reflexes of the Gastrointestinal Tract
Gastrointestinal tract
The human gastrointestinal tract refers to the stomach and intestine, and sometimes to all the structures from the mouth to the anus. ....

 include the Gastrocolic reflex
Gastrocolic reflex
The gastrocolic reflex or gastrocolic response is one of a number of physiological reflexes controlling the motility, or peristalsis, of the gastrointestinal tract. It involves an increase in motility of the colon in response to stretch in the stomach and byproducts of digestion in the small...

 and the Colonoileal reflex.
Enterogastric reflex activation thus, causes decreased motility.

Emptying inhibitory factors are-
Duodenal acidic pH,
Duodenal distension,
Duodenal hypertonicity,
sympathetic stimulation,
Intense pain

Emptying stimulatory factors are-
Parasympathetic stimulation,
Increased volume and fluidity of gastric contents.
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