EF-Ts
Encyclopedia
EF-Ts is one of the prokaryotic elongation factors
.
EF-Ts serves as the guanine
nucleotide exchange factor
for EF-Tu
(elongation factor thermo unstable), catalyzing the release of guanosine diphosphate
from EF-Tu. This enables EF-Tu to bind to a new guanosine triphosphate
molecule, release EF-Ts, and go on to catalyze another aminoacyl tRNA addition.
Prokaryotic elongation factors
In prokaryotes, three elongation factors are required for translation: EF-Tu, EF-Ts, and EF-G.*EF-Tu mediates the entry of the aminoacyl tRNA into a free site of the ribosome....
.
EF-Ts serves as the guanine
Guanine
Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine . In DNA, guanine is paired with cytosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with...
nucleotide exchange factor
Nucleotide exchange factor
Nucleotide exchange factors are proteins that stimulate the exchange of nucleoside diphosphates for nucleoside triphosphates bound to other proteins.-Function:...
for EF-Tu
EF-Tu
EF-Tu is one of the prokaryotic elongation factors.The prokaryotic factor EF-Tu mediates the entry of the aminoacyl-tRNA into a free site of the ribosome. EF-Tu functions by binding an aminoacylated, or charged, tRNA molecule in the cytoplasm...
(elongation factor thermo unstable), catalyzing the release of guanosine diphosphate
Guanosine diphosphate
Guanosine diphosphate, abbreviated GDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase guanine....
from EF-Tu. This enables EF-Tu to bind to a new guanosine triphosphate
Guanosine triphosphate
Guanosine-5'-triphosphate is a purine nucleoside triphosphate. It can act as a substrate for the synthesis of RNA during the transcription process...
molecule, release EF-Ts, and go on to catalyze another aminoacyl tRNA addition.