Dorothy Jordan Lloyd
Encyclopedia
Dorothy Jordan Lloyd was an early protein scientist who studied the interactions of water
Water
Water is a chemical substance with the chemical formula H2O. A water molecule contains one oxygen and two hydrogen atoms connected by covalent bonds. Water is a liquid at ambient conditions, but it often co-exists on Earth with its solid state, ice, and gaseous state . Water also exists in a...

 with protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

s, particularly gelatin
Gelatin
Gelatin is a translucent, colorless, brittle , flavorless solid substance, derived from the collagen inside animals' skin and bones. It is commonly used as a gelling agent in food, pharmaceuticals, photography, and cosmetic manufacturing. Substances containing gelatin or functioning in a similar...

. She was also Director of the British Leather Manufacturers' Research Association. She was the first to propose that the structure
Tertiary structure
In biochemistry and molecular biology, the tertiary structure of a protein or any other macromolecule is its three-dimensional structure, as defined by the atomic coordinates.-Relationship to primary structure:...

 of globular protein
Globular protein
Globular proteins, or spheroproteins are one of the two main protein classes, comprising "globe"-like proteins that are more or less soluble in aqueous solutions...

s was maintained by hydrogen bond
Hydrogen bond
A hydrogen bond is the attractive interaction of a hydrogen atom with an electronegative atom, such as nitrogen, oxygen or fluorine, that comes from another molecule or chemical group. The hydrogen must be covalently bonded to another electronegative atom to create the bond...

s, an idea championed later by Linus Pauling
Linus Pauling
Linus Carl Pauling was an American chemist, biochemist, peace activist, author, and educator. He was one of the most influential chemists in history and ranks among the most important scientists of the 20th century...

 and others.

Early life

She was born in Birmingham
Birmingham
Birmingham is a city and metropolitan borough in the West Midlands of England. It is the most populous British city outside the capital London, with a population of 1,036,900 , and lies at the heart of the West Midlands conurbation, the second most populous urban area in the United Kingdom with a...

, the daughter of George Jordan Lloyd, surgeon and later professor of surgery at the University of Birmingham
University of Birmingham
The University of Birmingham is a British Redbrick university located in the city of Birmingham, England. It received its royal charter in 1900 as a successor to Birmingham Medical School and Mason Science College . Birmingham was the first Redbrick university to gain a charter and thus...

, and his wife, Marian Hampson Simpson. One of four children, she was educated at the King Edward VI High School for Girls
King Edward VI High School for Girls
King Edward VI High School for Girls is an independent secondary school in Edgbaston, Birmingham, England. It is part of the Foundation of the Schools of King Edward VI in Birmingham and occupies the same site as, and is twinned with, King Edward's School...

, Birmingham
Birmingham
Birmingham is a city and metropolitan borough in the West Midlands of England. It is the most populous British city outside the capital London, with a population of 1,036,900 , and lies at the heart of the West Midlands conurbation, the second most populous urban area in the United Kingdom with a...

, and entered Newnham College, Cambridge
Newnham College, Cambridge
Newnham College is a women-only constituent college of the University of Cambridge, England.The college was founded in 1871 by Henry Sidgwick, and was the second Cambridge college to admit women after Girton College...

, in 1908. She was placed in the first class in part one of the natural sciences tripos in 1910 and in part two (zoology) in 1912, was a Bathurst student, and became the third Newnham fellow (1914–21). She worked for a time at Cambridge
Cambridge
The city of Cambridge is a university town and the administrative centre of the county of Cambridgeshire, England. It lies in East Anglia about north of London. Cambridge is at the heart of the high-technology centre known as Silicon Fen – a play on Silicon Valley and the fens surrounding the...

 on problems of regeneration and osmotic phenomena in muscle, and this led her to a study of osmotic phenomena in simpler non-living colloidal systems. Her researches were interrupted by the First World War when she investigated — for the Medical Research Committee - substitute culture media for bacteriology
Bacteriology
Bacteriology is the study of bacteria. This subdivision of microbiology involves the identification, classification, and characterization of bacterial species...

, and the causes and prevention of ropiness in bread.

Research and Later Life

She accepted an invitation from R. H. Pickard in 1921 to join the newly formed British Leather Manufacturers' Research Association. While maintaining her interest in fundamental research (particularly into the behaviour of protein fibres in aqueous systems), she rapidly acquired an insight into the art of leather manufacture, and introduced many methods of control which have since become normal tannery
Tanning
Tanning is the making of leather from the skins of animals which does not easily decompose. Traditionally, tanning used tannin, an acidic chemical compound from which the tanning process draws its name . Coloring may occur during tanning...

 practice. In 1927 she succeeded Pickard as director, and was, until her death, the only woman leading such an association for industrial research. In spite of many set-backs, including the destruction of new laboratories by German bombing in 1940, support for the association increased under her directorship, and it was recognized as an integral part of the industry. She served on the councils and committees of many societies, including the executive committee of the International Society of Leather
Leather
Leather is a durable and flexible material created via the tanning of putrescible animal rawhide and skin, primarily cattlehide. It can be produced through different manufacturing processes, ranging from cottage industry to heavy industry.-Forms:...

 Trades' Chemists. In 1939 she was awarded the Fraser Muir Moffat medal by the Tanners' Council of America for her contributions to leather chemistry. She was also vice-president of the Royal Institute of Chemistry
Royal Institute of Chemistry
The Royal Institute of Chemistry was a British scientific organisation.Founded in 1877 as the Institute of Chemistry of Great Britain, its role was to focus on qualifications and the professional status of chemists, and its aim was to ensure that consulting and analytical chemists were properly...

 (1943–6) and a member of the Chemical Council.

Besides many contributions to scientific journals, Dorothy Jordan Lloyd was the author of The Chemistry of the Proteins (1926; 2nd edn, with Agnes Shore, 1938), and planned and contributed to Progress in Leather Science, 1920–45 (3 vols., 1946–8), which became one of the world's foremost textbooks on leather technology.

A keen mountaineer, in 1928 Dorothy Jordan Lloyd achieved the distinction of making the first ascent and descent in one day of the Mittellegi Ridge of the Eiger
Eiger
The Eiger is a mountain in the Bernese Alps in Switzerland. It is the easternmost peak of a ridge crest that extends across the Mönch to the Jungfrau at 4,158 m...

. She died, unmarried, at Kenilworth Lodge, Great Bookham, Surrey
Surrey
Surrey is a county in the South East of England and is one of the Home Counties. The county borders Greater London, Kent, East Sussex, West Sussex, Hampshire and Berkshire. The historic county town is Guildford. Surrey County Council sits at Kingston upon Thames, although this has been part of...

, on 21 November 1946.

Further reading

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