Dennis Bray
Encyclopedia
Dennis Bray is an active emeritus professor at University of Cambridge
. His group is also part of the Oxford Centre for Integrative Systems Biology. After a first career in Neurobiology, working on cell growth and movement, Dennis Bray moved in Cambridge to develop computational models of cell signaling
, in particular in relation to bacterial chemotaxis
.
On November 3, 2006, he was awarded the Microsoft European Science Award for his work on chemotaxis
of E. coli
.
University of Cambridge
The University of Cambridge is a public research university located in Cambridge, United Kingdom. It is the second-oldest university in both the United Kingdom and the English-speaking world , and the seventh-oldest globally...
. His group is also part of the Oxford Centre for Integrative Systems Biology. After a first career in Neurobiology, working on cell growth and movement, Dennis Bray moved in Cambridge to develop computational models of cell signaling
Cell signaling
Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue...
, in particular in relation to bacterial chemotaxis
Chemotaxis
Chemotaxis is the phenomenon in which somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food by swimming towards the highest concentration of food molecules,...
.
On November 3, 2006, he was awarded the Microsoft European Science Award for his work on chemotaxis
Chemotaxis
Chemotaxis is the phenomenon in which somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food by swimming towards the highest concentration of food molecules,...
of E. coli
Escherichia coli
Escherichia coli is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms . Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans, and are occasionally responsible for product recalls...
.
Books
- Wetware: A Computer in Every Living Cell (2009) ISBN 0300141734, ISBN 978-0300141733
- Essential Cell Biology (2003) (with Bruce Alberts, Karen Hopkin, Alexander Jonhson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter) ISBN 081533480X, ISBN 978-0815334804
- Cell Movements: From Molecules to Motility (2000) ISBN 0815332823, ISBN 978-0815332824
- Essential Cell Biology: An Introduction to the Molecular Biology of the Cell (1997) (with Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter) ISBN 0815329717, ISBN 978-0815329718
- Molecular Biology of the Cell (1994) (with Bruce Alberts, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson) ISBN 0815319274, ISBN 978-0815319276
- Cell Movements (1992) ISBN 0815307179, ISBN 978-0815307174
- Molecular Biology of the Cell (1989) (with Bruce Alberts, Keith Roberts, Julian Lewis, Martin Raff) ISBN 0824036956, ISBN 9780824036959
Main scientific publications
- Bray D (1970) Surface movements during growth of single explanted neurons. Proc Natl Acad Sci USAProceedings of the National Academy of SciencesThe Proceedings of the National Academy of Sciences of the United States of America, usually referred to as PNAS, is the official journal of the United States National Academy of Sciences...
, 65: 905 - Bray D, Shite JG (1988) Cortical flow in animal cells. ScienceScience (journal)Science is the academic journal of the American Association for the Advancement of Science and is one of the world's top scientific journals....
, 239: 883-888 - Bray D (1995) Protein molecules as computational elements in living cells. NatureNature (journal)Nature, first published on 4 November 1869, is ranked the world's most cited interdisciplinary scientific journal by the Science Edition of the 2010 Journal Citation Reports...
, 376: 307-312 - Bray D, Levin MD, Morton-Firth CJ (1998) Receptor clustering as a cellular mechanism to control sensitivity. NatureNature (journal)Nature, first published on 4 November 1869, is ranked the world's most cited interdisciplinary scientific journal by the Science Edition of the 2010 Journal Citation Reports...
, 393: 85-88
Mention in Popular Science
Professor Franklin M. Harold writes "The theme [of a protein's shape and functionality being altered by interaction with its environment] comes with numerous variations, some of which are discussed in a thought-provoking article by Dennis Bray [author references Dr. Bray's 1995 article] that examines proteins as information-processing devices."External links
- Oxford Centre for Integrative Systems Biology
- Department for Dennis Bray at University of CambridgeUniversity of CambridgeThe University of Cambridge is a public research university located in Cambridge, United Kingdom. It is the second-oldest university in both the United Kingdom and the English-speaking world , and the seventh-oldest globally...
- Review Article version of Bray D (1995) Protein molecules as computational elements in living cells.