Clinical Cancer Research
Encyclopedia
Clinical Cancer Research is a peer-reviewed
medical journal
on clinical oncology
published by the American Association for Cancer Research
.
s with clinical interests and to those research
ers exploring new therapies
.
The AACR decided to publish this journal to respond to the need to unite research exploring clinical applications of the molecular revolution in the understanding of cell growth
, proliferation, differentiation, and death. The journal also responded to the need for interdisciplinary
collaborations.
By December 1, 1994, 128 manuscript
s had been submitted for publication by investigators representing a variety of clinical and laboratory disciplines not only from the United States
but also from the international research community. In 1998 the number of manuscripts submitted had risen from 500 in the first year to almost 800. The journal reported an acceptance rate of 52% at that time. With the aim to publish only papers of high quality, the Senior Editors agreed to increase the stringency of review.
There is a lot that we still do not know about cancer and medical technologies have changed the way we look at this disease, therefore, the proposed areas of research for this journal have been helpful to support new research. The areas that were defined at the beginning included subspecialties of clinical oncology including medical and hematological oncology, radiation therapy
, pediatric oncology, pathology
, surgical oncology, and clinical genetics
. The applications of the disciplines of pharmacology
, immunology
, cell biology
, and molecular genetics
to intervention in human cancer were also included.
Since its beginnings, Clinical Cancer Research has been focused on publishing innovative clinical research and translational research which bridges the laboratory and the clinic. One of the main interests of Clinical Cancer Research is on clinical trails that evaluate new treatments together with research on pharmacology and molecular alterations or biomarkers that predict response or resistance to treatment. It therefore reports those new studies that can transform research findings into actual clinical interventions in the management of both cancer patients and individuals at risk of developing cancer.
Another priority for Clinical Cancer Research is laboratory and animal studies
of new drugs as well as molecule-targeted agents with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of the malignant phenotype
, and metastatic disease.
In 1998 the journal was included in Index Medicus
and MEDLINE
. That same year, the Institute for Scientific Information
selected Clinical Cancer Research for extended coverage in ISI products. Tables of contents are thus indexed in the Science Citation Index
and included in SciSearch, Research Alert, and Current Contents
. In 1999, the United States National Library of Medicine
agreed to index articles back to Volume 1.
Clinical Cancer Research is in the top 25% oncology journals along with the other publications from AACR: Cancer Research
, Molecular Cancer Research
, Cancer Epidemiology
, Biomarkers & Prenvention, Molecular Cancer Therapeutics, and Cancer Prevention Research.
Peer review
Peer review is a process of self-regulation by a profession or a process of evaluation involving qualified individuals within the relevant field. Peer review methods are employed to maintain standards, improve performance and provide credibility...
medical journal
Medical journal
A public health journal is a scientific journal devoted to the field of public health, including epidemiology, biostatistics, and health care . Public health journals, like most scientific journals, are peer-reviewed...
on clinical oncology
Oncology
Oncology is a branch of medicine that deals with cancer...
published by the American Association for Cancer Research
American Association for Cancer Research
The American Association for Cancer Research is the world's oldest and largest professional association to advancing cancer research. Based in Philadelphia, AACR focuses on all aspects of cancer research including basic, clinical and translational research into the etiology, prevention, diagnosis,...
.
History of the journal
Clinical Cancer Research was first published in January 1995 and its mission was to publish original articles describing clinical research on the cellular and molecular characterization, prevention, diagnosis, and therapy of human cancer. Also, part of its mission since then has been to develop an educational function by offering information of interest to basic scientistScientist
A scientist in a broad sense is one engaging in a systematic activity to acquire knowledge. In a more restricted sense, a scientist is an individual who uses the scientific method. The person may be an expert in one or more areas of science. This article focuses on the more restricted use of the word...
s with clinical interests and to those research
Research
Research can be defined as the scientific search for knowledge, or as any systematic investigation, to establish novel facts, solve new or existing problems, prove new ideas, or develop new theories, usually using a scientific method...
ers exploring new therapies
Therapy
This is a list of types of therapy .* Adventure therapy* Animal-assisted therapy* Aquatic therapy* Aromatherapy* Art and dementia* Art therapy* Authentic Movement* Behavioral therapy* Bibliotherapy* Buteyko Method* Chemotherapy...
.
The AACR decided to publish this journal to respond to the need to unite research exploring clinical applications of the molecular revolution in the understanding of cell growth
Cell growth
The term cell growth is used in the contexts of cell development and cell division . When used in the context of cell division, it refers to growth of cell populations, where one cell grows and divides to produce two "daughter cells"...
, proliferation, differentiation, and death. The journal also responded to the need for interdisciplinary
Interdisciplinarity
Interdisciplinarity involves the combining of two or more academic fields into one single discipline. An interdisciplinary field crosses traditional boundaries between academic disciplines or schools of thought, as new needs and professions have emerged....
collaborations.
By December 1, 1994, 128 manuscript
Manuscript
A manuscript or handwrite is written information that has been manually created by someone or some people, such as a hand-written letter, as opposed to being printed or reproduced some other way...
s had been submitted for publication by investigators representing a variety of clinical and laboratory disciplines not only from the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
but also from the international research community. In 1998 the number of manuscripts submitted had risen from 500 in the first year to almost 800. The journal reported an acceptance rate of 52% at that time. With the aim to publish only papers of high quality, the Senior Editors agreed to increase the stringency of review.
There is a lot that we still do not know about cancer and medical technologies have changed the way we look at this disease, therefore, the proposed areas of research for this journal have been helpful to support new research. The areas that were defined at the beginning included subspecialties of clinical oncology including medical and hematological oncology, radiation therapy
Radiation therapy
Radiation therapy , radiation oncology, or radiotherapy , sometimes abbreviated to XRT or DXT, is the medical use of ionizing radiation, generally as part of cancer treatment to control malignant cells.Radiation therapy is commonly applied to the cancerous tumor because of its ability to control...
, pediatric oncology, pathology
Pathology
Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....
, surgical oncology, and clinical genetics
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....
. The applications of the disciplines of pharmacology
Pharmacology
Pharmacology is the branch of medicine and biology concerned with the study of drug action. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function...
, immunology
Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...
, cell biology
Cell biology
Cell biology is a scientific discipline that studies cells – their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division and death. This is done both on a microscopic and molecular level...
, and molecular genetics
Molecular genetics
Molecular genetics is the field of biology and genetics that studies the structure and function of genes at a molecular level. The field studies how the genes are transferred from generation to generation. Molecular genetics employs the methods of genetics and molecular biology...
to intervention in human cancer were also included.
Since its beginnings, Clinical Cancer Research has been focused on publishing innovative clinical research and translational research which bridges the laboratory and the clinic. One of the main interests of Clinical Cancer Research is on clinical trails that evaluate new treatments together with research on pharmacology and molecular alterations or biomarkers that predict response or resistance to treatment. It therefore reports those new studies that can transform research findings into actual clinical interventions in the management of both cancer patients and individuals at risk of developing cancer.
Another priority for Clinical Cancer Research is laboratory and animal studies
Animal studies
Animal studies is a recently recognized field in which animals are studied in a variety of cross-disciplinary ways. Scholars from fields as diverse as: art history, anthropology, biology, film studies, geography, history, psychology, literary studies, museology, philosophy, and sociology; and from...
of new drugs as well as molecule-targeted agents with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of the malignant phenotype
Phenotype
A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior...
, and metastatic disease.
In 1998 the journal was included in Index Medicus
Index medicus
Index Medicus is a comprehensive index of medical scientific journal articles, published since 1879. It was initiated by John Shaw Billings, head of the Library of the Surgeon General's Office, United States Army...
and MEDLINE
MEDLINE
MEDLINE is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care...
. That same year, the Institute for Scientific Information
Institute for Scientific Information
The Institute for Scientific Information was founded by Eugene Garfield in 1960. It was acquired by Thomson Scientific & Healthcare in 1992, became known as Thomson ISI and now is part of the Healthcare & Science business of the multi-billion dollar Thomson Reuters Corporation.ISI offered...
selected Clinical Cancer Research for extended coverage in ISI products. Tables of contents are thus indexed in the Science Citation Index
Science Citation Index
The Science Citation Index is a citation index originally produced by the Institute for Scientific Information and created by Eugene Garfield in 1960, which is now owned by Thomson Reuters. The larger version covers more than 6,500 notable and significant journals, across 150 disciplines, from ...
and included in SciSearch, Research Alert, and Current Contents
Current Contents
Current Contents is a rapid alerting service database from the Institute for Scientific Information, now part of Thomson Reuters, that is published online and in several different printed subject sections.-History:...
. In 1999, the United States National Library of Medicine
United States National Library of Medicine
The United States National Library of Medicine , operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is a division of the National Institutes of Health...
agreed to index articles back to Volume 1.
Clinical Cancer Research is in the top 25% oncology journals along with the other publications from AACR: Cancer Research
Cancer Research (journal)
Cancer Research is a scientific journal published by the American Association for Cancer Research. Its focus is original research papers relating to cancer and cancer-related biomedical sciences. The first edition was published in 1941.-Indexing:...
, Molecular Cancer Research
Molecular Cancer Research
Molecular Cancer Research is a monthly peer reviewed academic journal published by the American Association for Cancer Research.Prior to September 2002 it was known as Cell Growth & Differentiation.- External links :*...
, Cancer Epidemiology
Cancer Epidemiology (journal)
The Cancer Epidemiology is a peer reviewed journal devoted to epidemiological cancer research....
, Biomarkers & Prenvention, Molecular Cancer Therapeutics, and Cancer Prevention Research.