Charge remote fragmentation
Encyclopedia
Charge remote fragmentation is a type of covalent bond
breaking that occurs in a gas phase ion
in which the cleaved bond is not adjacent to the location of the charge. This fragmentation can be observed using tandem mass spectrometry
.
Covalent bond
A covalent bond is a form of chemical bonding that is characterized by the sharing of pairs of electrons between atoms. The stable balance of attractive and repulsive forces between atoms when they share electrons is known as covalent bonding....
breaking that occurs in a gas phase ion
Ion
An ion is an atom or molecule in which the total number of electrons is not equal to the total number of protons, giving it a net positive or negative electrical charge. The name was given by physicist Michael Faraday for the substances that allow a current to pass between electrodes in a...
in which the cleaved bond is not adjacent to the location of the charge. This fragmentation can be observed using tandem mass spectrometry
Tandem mass spectrometry
Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages.-Tandem MS instruments:...
.