Carl Schmidt (chemist)
Encyclopedia
Carl Ernst Heinrich Schmidt (13 June 1822 - 27 February 1894), also known in Russia as Karl Genrikhovich Schmidt was a Livonian chemist
. He determined the typical crystallization
patterns of many important biochemicals such as uric acid
, oxalic acid
and its salts, lactic acid
, cholesterin, stearin
, etc. He analyzed muscle fiber and chitin
. He showed that animal and plant cell
constituents are chemically similar and studied reactions of calcium albuminates. He studied alcoholic fermentation and the chemistry of metabolism
and digestion. He discovered hydrochloric acid
in gastric juice and its chemical interaction with pepsin
. He studied bile
and pancreatic juice
s. Some of this work was done with Friedrich Bidder. He studied chemical changes in blood associated with cholera
, dysentery
, diabetes, and arsenic poisoning
.
Schmidt received his PhD
in 1844 from the University of Gießen under Justus von Liebig
. In 1850 Schmidt had been named Professor of Pharmacy
at Dorpat and in 1851 he was appointed Professor of Chemistry in the mathematical and physical division on the University of Dorpat. He was a corresponding member (1873) of the Saint Petersburg Academy of Sciences (today Russian Academy of Sciences
). He was the president of the Estonian Naturalists' Society
in 1894. Schmidt is notable as the PhD advisor of the Nobel Prize
winner Wilhelm Ostwald
.
Chemistry
Chemistry is the science of matter, especially its chemical reactions, but also its composition, structure and properties. Chemistry is concerned with atoms and their interactions with other atoms, and particularly with the properties of chemical bonds....
. He determined the typical crystallization
Crystallization
Crystallization is the process of formation of solid crystals precipitating from a solution, melt or more rarely deposited directly from a gas. Crystallization is also a chemical solid–liquid separation technique, in which mass transfer of a solute from the liquid solution to a pure solid...
patterns of many important biochemicals such as uric acid
Uric acid
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and acid urates such as ammonium acid urate. Uric acid is created when the body breaks down purine nucleotides. High blood concentrations of uric acid...
, oxalic acid
Oxalic acid
Oxalic acid is an organic compound with the formula H2C2O4. This colourless solid is a dicarboxylic acid. In terms of acid strength, it is about 3,000 times stronger than acetic acid. Oxalic acid is a reducing agent and its conjugate base, known as oxalate , is a chelating agent for metal cations...
and its salts, lactic acid
Lactic acid
Lactic acid, also known as milk acid, is a chemical compound that plays a role in various biochemical processes and was first isolated in 1780 by the Swedish chemist Carl Wilhelm Scheele. Lactic acid is a carboxylic acid with the chemical formula C3H6O3...
, cholesterin, stearin
Stearin
Stearin , or tristearin, or glyceryl tristearate is a triglyceride, a glyceryl ester of stearic acid, derived from animal fats created as a byproduct of processing beef. It can also be found in tropical plants such as palm. It is used as tallow in the manufacture of candles and soap. In the...
, etc. He analyzed muscle fiber and chitin
Chitin
Chitin n is a long-chain polymer of a N-acetylglucosamine, a derivative of glucose, and is found in many places throughout the natural world...
. He showed that animal and plant cell
Plant cell
Plant cells are eukaryotic cells that differ in several key respects from the cells of other eukaryotic organisms. Their distinctive features include:...
constituents are chemically similar and studied reactions of calcium albuminates. He studied alcoholic fermentation and the chemistry of metabolism
Metabolism
Metabolism is the set of chemical reactions that happen in the cells of living organisms to sustain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments. Metabolism is usually divided into two categories...
and digestion. He discovered hydrochloric acid
Hydrochloric acid
Hydrochloric acid is a solution of hydrogen chloride in water, that is a highly corrosive, strong mineral acid with many industrial uses. It is found naturally in gastric acid....
in gastric juice and its chemical interaction with pepsin
Pepsin
Pepsin is an enzyme whose precursor form is released by the chief cells in the stomach and that degrades food proteins into peptides. It was discovered in 1836 by Theodor Schwann who also coined its name from the Greek word pepsis, meaning digestion...
. He studied bile
Bile
Bile or gall is a bitter-tasting, dark green to yellowish brown fluid, produced by the liver of most vertebrates, that aids the process of digestion of lipids in the small intestine. In many species, bile is stored in the gallbladder and upon eating is discharged into the duodenum...
and pancreatic juice
Pancreatic juice
Pancreatic juice is a liquid secreted by the pancreas, which contains a variety of enzymes, including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, and amylase....
s. Some of this work was done with Friedrich Bidder. He studied chemical changes in blood associated with cholera
Cholera
Cholera is an infection of the small intestine that is caused by the bacterium Vibrio cholerae. The main symptoms are profuse watery diarrhea and vomiting. Transmission occurs primarily by drinking or eating water or food that has been contaminated by the diarrhea of an infected person or the feces...
, dysentery
Dysentery
Dysentery is an inflammatory disorder of the intestine, especially of the colon, that results in severe diarrhea containing mucus and/or blood in the faeces with fever and abdominal pain. If left untreated, dysentery can be fatal.There are differences between dysentery and normal bloody diarrhoea...
, diabetes, and arsenic poisoning
Arsenic poisoning
Arsenic poisoning is a medical condition caused by increased levels of the element arsenic in the body. Arsenic interferes with cellular longevity by allosteric inhibition of an essential metabolic enzyme...
.
Schmidt received his PhD
Doctor of Philosophy
Doctor of Philosophy, abbreviated as Ph.D., PhD, D.Phil., or DPhil , in English-speaking countries, is a postgraduate academic degree awarded by universities...
in 1844 from the University of Gießen under Justus von Liebig
Justus von Liebig
Justus von Liebig was a German chemist who made major contributions to agricultural and biological chemistry, and worked on the organization of organic chemistry. As a professor, he devised the modern laboratory-oriented teaching method, and for such innovations, he is regarded as one of the...
. In 1850 Schmidt had been named Professor of Pharmacy
Pharmacy
Pharmacy is the health profession that links the health sciences with the chemical sciences and it is charged with ensuring the safe and effective use of pharmaceutical drugs...
at Dorpat and in 1851 he was appointed Professor of Chemistry in the mathematical and physical division on the University of Dorpat. He was a corresponding member (1873) of the Saint Petersburg Academy of Sciences (today Russian Academy of Sciences
Russian Academy of Sciences
The Russian Academy of Sciences consists of the national academy of Russia and a network of scientific research institutes from across the Russian Federation as well as auxiliary scientific and social units like libraries, publishers and hospitals....
). He was the president of the Estonian Naturalists' Society
Estonian Naturalists' Society
Estonian Naturalists' Society is the oldest Estonia-based society of naturalists. It was founded in 1853, and since establishing has been the major scientific organisation focusing on natural history of Estonia....
in 1894. Schmidt is notable as the PhD advisor of the Nobel Prize
Nobel Prize
The Nobel Prizes are annual international awards bestowed by Scandinavian committees in recognition of cultural and scientific advances. The will of the Swedish chemist Alfred Nobel, the inventor of dynamite, established the prizes in 1895...
winner Wilhelm Ostwald
Wilhelm Ostwald
Friedrich Wilhelm Ostwald was a Baltic German chemist. He received the Nobel Prize in Chemistry in 1909 for his work on catalysis, chemical equilibria and reaction velocities...
.