Blood island
Encyclopedia
Blood islands are structures in the developing embryo
Embryo
An embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination...

 which lead to many different parts of the circulatory system.

They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction
Liquefaction
Liquefaction may refer to:* Liquefaction, the general process of becoming liquid* Soil liquefaction, the process by which sediments become suspended* Liquefaction of gases in physics, chemistry, and thermal engineering* Liquefactive necrosis in pathology...

 of the central part of the syncytium
Syncytium
In biology, a syncytium is a large cell-like structure; filled with cytoplasm and containing many nuclei. Most cells in eukaryotic organisms have a single nucleus; syncytia are specialized forms used by various organisms.The term may also refer to cells that are connected by specialized membrane...

 into plasma
Blood plasma
Blood plasma is the straw-colored liquid component of blood in which the blood cells in whole blood are normally suspended. It makes up about 55% of the total blood volume. It is the intravascular fluid part of extracellular fluid...

. The lumen
Lumen (anatomy)
A lumen in biology is the inside space of a tubular structure, such as an artery or intestine...

 of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium
Endothelium
The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall. These cells are called endothelial cells. Endothelial cells line the entire circulatory system, from the heart...

.

The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin
Hemoglobin
Hemoglobin is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates, with the exception of the fish family Channichthyidae, as well as the tissues of some invertebrates...

 gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide.

Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta
Dorsal aorta
Each primitive aorta receives anteriorly a vein—the vitelline vein—from the yolk-sac, and is prolonged backward on the lateral aspect of the notochord under the name of the dorsal aorta....

.

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