Arvid Lindau
Encyclopedia
Arvid Lindau was a Swedish pathologist born in Malmö
. During his career he published more than forty papers on pathology, neurology
, and bacteriology
. At the Institute of Pathological Anatomy
in Lund
he wrote an important thesis titled Studien über Kleinhirncysten. Bau, Pathogenese und Beziehungen zur Angiomatosae retinae, in which he described the relationship between cerebellar
cysts and their correlation to tumors (angiomata) of the retina
.
In 1926, Lindau was the first to describe a coherent link between the retinal, cerebellar and visceral components of a disease he called "angiomatosis of the central nervous system". This disease is characterized by tumors of the retina and the brain, along with cysts of several visceral organs such as the kidneys, pancreas
, and adrenal gland
s. Lindau's research soon attracted the attention of famed neurosurgeon Harvey Cushing
, who named the disorder, "Lindau's disease". However it wasn't until 1964, that early 20th century research conducted by ophthalmologist Eugen von Hippel
on retinal angiomata became more apparent. Today the disease is named after both men, and is called Von Hippel-Lindau disease
.
Malmö
Malmö , in the southernmost province of Scania, is the third most populous city in Sweden, after Stockholm and Gothenburg.Malmö is the seat of Malmö Municipality and the capital of Skåne County...
. During his career he published more than forty papers on pathology, neurology
Neurology
Neurology is a medical specialty dealing with disorders of the nervous system. Specifically, it deals with the diagnosis and treatment of all categories of disease involving the central, peripheral, and autonomic nervous systems, including their coverings, blood vessels, and all effector tissue,...
, and bacteriology
Bacteriology
Bacteriology is the study of bacteria. This subdivision of microbiology involves the identification, classification, and characterization of bacterial species...
. At the Institute of Pathological Anatomy
Anatomy
Anatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...
in Lund
Lund
-Main sights:During the 12th and 13th centuries, when the town was the seat of the archbishop, many churches and monasteries were built. At its peak, Lund had 27 churches, but most of them were demolished as result of the Reformation in 1536. Several medieval buildings remain, including Lund...
he wrote an important thesis titled Studien über Kleinhirncysten. Bau, Pathogenese und Beziehungen zur Angiomatosae retinae, in which he described the relationship between cerebellar
Cerebellum
The cerebellum is a region of the brain that plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language, and in regulating fear and pleasure responses, but its movement-related functions are the most solidly established...
cysts and their correlation to tumors (angiomata) of the retina
Retina
The vertebrate retina is a light-sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera. Light striking the retina initiates a cascade of chemical and electrical...
.
In 1926, Lindau was the first to describe a coherent link between the retinal, cerebellar and visceral components of a disease he called "angiomatosis of the central nervous system". This disease is characterized by tumors of the retina and the brain, along with cysts of several visceral organs such as the kidneys, pancreas
Pancreas
The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as a digestive organ, secreting pancreatic juice containing digestive enzymes that assist...
, and adrenal gland
Adrenal gland
In mammals, the adrenal glands are endocrine glands that sit atop the kidneys; in humans, the right suprarenal gland is triangular shaped, while the left suprarenal gland is semilunar shaped...
s. Lindau's research soon attracted the attention of famed neurosurgeon Harvey Cushing
Harvey Cushing
Harvey Williams Cushing, M.D. , was an American neurosurgeon and a pioneer of brain surgery, and the first to describe Cushing's syndrome...
, who named the disorder, "Lindau's disease". However it wasn't until 1964, that early 20th century research conducted by ophthalmologist Eugen von Hippel
Eugen von Hippel
Eugen von Hippel was a German ophthalmologist who was born in Königsberg. He studied medicine in Heidelberg under ophthalmologist Theodor Leber and neurologist Wilhelm Heinrich Erb . In 1897 he attained the title of "professor extraordinary" at Heidelberg, and in 1909 became a professor at the...
on retinal angiomata became more apparent. Today the disease is named after both men, and is called Von Hippel-Lindau disease
Von Hippel-Lindau disease
Von Hippel–Lindau is a rare, autosomal dominant genetic condition in which hemangioblastomas are found in the cerebellum, spinal cord, kidney and retina. These are associated with several pathologies including renal angioma, renal cell carcinoma and pheochromocytoma...
.
External sources
- Information on VHL disease
- VHL Family Alliance (biography of Arvid Lindau)