Arthur Groenouw
Encyclopedia
Arthur Groenouw was a German ophthalmologist born in Bosatz, a village near Ratibor
Racibórz
Racibórz is a town in southern Poland with 60,218 inhabitants situated in the Silesian Voivodeship , previously in Katowice Voivodeship...

. He studied medicine in Breslau, and was an assistant to physiologist Rudolf Heidenhain
Rudolf Heidenhain
Rudolf Peter Heinrich Heidenhain was a German physiologist who was born in Marienwerder, East Prussia . He studied medicine at the Universities of Halle and Berlin. After receiving his doctorate, he remained in Berlin as an assistant to Emil du Bois-Reymond...

 (1834-1897) and ophthalmologist Wilhelm Uhthoff
Wilhelm Uhthoff
Wilhelm Uhthoff was a German ophthalmologist who was born in Klein-Warin. In 1877 earned his doctorate at the University of Berlin, and later became a professor of ophthalmology at the Universities of Marburg and Breslau , where he succeeded Carl Friedrich Richard Förster .Uhthoff specialized in...

 (1853-1927). In 1892 he was habilitated for ophthalmology in Breslau.

In 1890 Groenouw described two different types of corneal dystrophy
Corneal dystrophy
Corneal dystrophy is a group of disorders, characterised by a noninflammatory, inherited, bilateral opacity of the transparent front part of the eye called the cornea.The distrophies could be subdivided based on specie affected:...

, of which he published in an article named Knötchenförmige Hornhauttrübungen (noduli corneae). At the time he believed that they were variations of the same disease. Subsequently, his findings on corneal dystrophy were classified as two separate syndromes:
  • Groenouw Type I
    Granular corneal dystrophy type I
    Granular corneal dystrophy type I is a rare form of human corneal dystrophy. It is caused by mutations in TGFBI gene encoding keratoepithelin....

    : Granula
    Granula
    Granula was the first manufactured breakfast cereal invented by James Caleb Jackson in 1863. Granula was an early version of Grape-Nuts, consisting of heavy grains of bran-rich Graham flour. The grains had to be soaked overnight before use....

    r type of corneal dystrophy. Characterized by discrete grey opacities scattered over the surface of the cornea.
  • Groenouw Type II
    Macular corneal dystrophy
    Macular corneal dystrophy is a rare pathological condition affecting the stroma of cornea. The first signs are usually noticed in the first decade of life, and progress afterwards, with opacities developing in the cornea and attacks of pain...

    : Macular type of corneal dystrophy. Characterized by greyish white opaque granules with sharp borders, mostly in central part of cornea
    Cornea
    The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...

    .
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