Granular corneal dystrophy type I
Encyclopedia
Granular corneal dystrophy type I (also corneal dystrophy Groenouw type I) is a rare form of human corneal dystrophy
. It is caused by mutations in TGFBI
gene encoding keratoepithelin.
It was first described by German ophthalmologist Arthur Groenouw
in 1890, with expanded accounts in the following years.
Corneal dystrophy (human)
Human corneal dystrophy is a group of disorders, characterised by a noninflammatory, inherited, bilateral opacity of the transparent front part of the human eye called the cornea...
. It is caused by mutations in TGFBI
TGFBI
Transforming growth factor, beta-induced, 68kDa, also known as TGFBI , is a protein which in humans is encoded by the TGFBI gene.- Function :...
gene encoding keratoepithelin.
It was first described by German ophthalmologist Arthur Groenouw
Arthur Groenouw
Arthur Groenouw was a German ophthalmologist born in Bosatz, a village near Ratibor. He studied medicine in Breslau, and was an assistant to physiologist Rudolf Heidenhain and ophthalmologist Wilhelm Uhthoff...
in 1890, with expanded accounts in the following years.