Arena Pharmaceuticals
Encyclopedia
Arena Pharmaceuticals, Inc. is a biopharmaceutical company located in San Diego, California
. The company is developing oral medications that target G-protein-coupled receptors. Currently none of the drugs is approved by the U.S. Food and Drug Administration, but several are in Phase I to III testing, namely (stand January 2009):
San Diego, California
San Diego is the eighth-largest city in the United States and second-largest city in California. The city is located on the coast of the Pacific Ocean in Southern California, immediately adjacent to the Mexican border. The birthplace of California, San Diego is known for its mild year-round...
. The company is developing oral medications that target G-protein-coupled receptors. Currently none of the drugs is approved by the U.S. Food and Drug Administration, but several are in Phase I to III testing, namely (stand January 2009):
- LorcaserinLorcaserinLorcaserin is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic. On 22 December 2009 a New Drug Application was submitted to the Food and Drug Administration in the United States and lorcaserin is pending approval...
, Phase III , indication: obesityObesityObesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems...
. - APD791, Phase I, indication: arterial thrombosis.
- APD916, entering Phase I, indication: pulmonary hypertensionPulmonary hypertensionIn medicine, pulmonary hypertension is an increase in blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries, together known as the lung vasculature, leading to shortness of breath, dizziness, fainting, and other symptoms, all of which are exacerbated by exertion...
. - Niacin receptor antagonist, Phase I, indication: arteriosclerosisArteriosclerosisArteriosclerosis refers to a stiffening of arteries.Arteriosclerosis is a general term describing any hardening of medium or large arteries It should not be confused with "arteriolosclerosis" or "atherosclerosis".Also known by the name "myoconditis" which is...
, (in conjunction with MerckMerck & Co.Merck & Co., Inc. , also known as Merck Sharp & Dohme or MSD outside the United States and Canada, is one of the largest pharmaceutical companies in the world. The Merck headquarters is located in Whitehouse Station, New Jersey, an unincorporated area in Readington Township...
) - APD597, Phase II, indication: diabetes type 2, (in conjunction with Ortho-McNeil-JanssenOrtho-McNeil-JanssenOrtho-McNeil-Janssen Pharmaceuticals, Inc is a healthcare company of Johnson & Johnson composed of two divisions:* Ortho-McNeil, based in Raritan, NJ ; the division is focused on primary care....
)