Amygdules or amygdales form when the gas bubbles or vesicles

Vesicular texture

Vesicular texture is a volcanic rock texture characterised by a rock being pitted with many cavities at its surface and inside. The texture is often found in extrusive aphanitic, or glassy, igneous rock...

 in volcanic lava

Lava

Lava refers both to molten rock expelled by a volcano during an eruption and the resulting rock after solidification and cooling. This molten rock is formed in the interior of some planets, including Earth, and some of their satellites. When first erupted from a volcanic vent, lava is a liquid at...

 (or other extrusive igneous rocks) are infilled with a secondary mineral

Mineral

A mineral is a naturally occurring solid chemical substance formed through biogeochemical processes, having characteristic chemical composition, highly ordered atomic structure, and specific physical properties. By comparison, a rock is an aggregate of minerals and/or mineraloids and does not...

 such as calcite

Calcite

Calcite is a carbonate mineral and the most stable polymorph of calcium carbonate . The other polymorphs are the minerals aragonite and vaterite. Aragonite will change to calcite at 380-470°C, and vaterite is even less stable.-Properties:...

, quartz

Quartz

Quartz is the second-most-abundant mineral in the Earth's continental crust, after feldspar. It is made up of a continuous framework of SiO4 silicon–oxygen tetrahedra, with each oxygen being shared between two tetrahedra, giving an overall formula SiO2. There are many different varieties of quartz,...

, chlorite

Chlorite group

The chlorites are a group of phyllosilicate minerals. Chlorites can be described by the following four endmembers based on their chemistry via substitution of the following four elements in the silicate lattice; Mg, Fe, Ni, and Mn....

 or one of the zeolite

Zeolite

Zeolites are microporous, aluminosilicate minerals commonly used as commercial adsorbents. The term zeolite was originally coined in 1756 by Swedish mineralogist Axel Fredrik Cronstedt, who observed that upon rapidly heating the material stilbite, it produced large amounts of steam from water that...

s. Amygdules usually form after the rock has been emplaced, and are often associated with low-temperature alteration. Amygdules may often be concentrically zoned. Rocks containing amygdules can be described as amygdaloidal.

The word is derived from the Latin (amygdala) and Greek (αμυγδαλή) words for almond, reflecting the typical shape of an infilled vesicle.

"Amygdule" is more common in US usage, while "amygdale" is more common in British usage.