ACAA2
Encyclopedia
3-Ketoacyl-CoA thiolase, mitochondrial also known as acetyl-Coenzyme A acyltransferase 2 is an enzyme
that in humans is encoded by the ACAA2 gene
.
Acetyl-Coenzyme A acyltransferase 2 is a acetyl-CoA C-acyltransferase
enzyme.
fatty acid beta oxidation
spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the ACAA2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Acetyl-Coenzyme A acyltransferase 2 is a acetyl-CoA C-acyltransferase
Acetyl-CoA C-acyltransferase
The final step of beta oxidation is the cleavage of 3-ketoacyl CoA by the thiol group of another molecule of CoA. This reaction is catalyzed by Acetyl-CoA C-acyltransferase...
enzyme.
Function
The encoded protein catalyzes the last step of the mitochondrialMitochondrion
In cell biology, a mitochondrion is a membrane-enclosed organelle found in most eukaryotic cells. These organelles range from 0.5 to 1.0 micrometers in diameter...
fatty acid beta oxidation
Beta oxidation
Beta oxidation is the process by which fatty acids, in the form of Acyl-CoA molecules, are broken down in mitochondria and/or in peroxisomes to generate Acetyl-CoA, the entry molecule for the Citric Acid cycle....
spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.