4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
Encyclopedia
In enzymology, a 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase is an enzyme
that catalyzes
the chemical reaction
-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + protein-disulfide
2-C-methyl-D-erythritol 2,4-cyclodiphosphate + protein-dithiol
The 3 substrates
of this enzyme are (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
(HMB-PP), H2O
, and protein disulfide, whereas its two products
are 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and protein dithiol.
This enzyme belongs to the family of oxidoreductase
s, specifically those acting on CH or CH2 group with a disulfide as acceptor. The systematic name of this enzyme class is (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating). This enzyme participates in biosynthesis of steroids.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that catalyzes
Catalysis
Catalysis is the change in rate of a chemical reaction due to the participation of a substance called a catalyst. Unlike other reagents that participate in the chemical reaction, a catalyst is not consumed by the reaction itself. A catalyst may participate in multiple chemical transformations....
the chemical reaction
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...
-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + protein-disulfide
2-C-methyl-D-erythritol 2,4-cyclodiphosphate + protein-dithiolThe 3 substrates
Substrate (biochemistry)
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate. In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or...
of this enzyme are (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate
-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate is an intermediate of the non-mevalonate pathway of isoprenoid biosynthesis...
(HMB-PP), H2O
Water
Water is a chemical substance with the chemical formula H2O. A water molecule contains one oxygen and two hydrogen atoms connected by covalent bonds. Water is a liquid at ambient conditions, but it often co-exists on Earth with its solid state, ice, and gaseous state . Water also exists in a...
, and protein disulfide, whereas its two products
Product (chemistry)
Product are formed during chemical reactions as reagents are consumed. Products have lower energy than the reagents and are produced during the reaction according to the second law of thermodynamics. The released energy comes from changes in chemical bonds between atoms in reagent molecules and...
are 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and protein dithiol.
This enzyme belongs to the family of oxidoreductase
Oxidoreductase
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule to another...
s, specifically those acting on CH or CH2 group with a disulfide as acceptor. The systematic name of this enzyme class is (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating). This enzyme participates in biosynthesis of steroids.