1954    First flight of the Boeing 367-80, prototype for both the Boeing 707 and C-135 series.

1958    Pan American Airways makes the first commercial flight of the Boeing 707 from New York City to Paris, France.

1962    An Air France Boeing 707 charter, Chateau de Sully crashes after an aborted takeoff from Paris-Orly Airport, killing 130.

1962    An Air France Boeing 707 jet crashes in bad weather in Guadeloupe, West Indies, killing 113.

1963    Pan Am Flight 214, a Boeing 707, is struck by positive lightning and crashes near Elkton, Maryland, United States, killing all 81 people on board.

1965    PIA Flight 705, a Pakistan International Airlines Boeing 720 – 040 B, crashes while descending to land at Cairo International Airport, killing 119 of the 125 passengers and crew.

1968    The only successful hijacking of an El Al aircraft takes place when a Boeing 707 carrying 10 crew and 38 passengers is taken over by three members of the Popular Front for the Liberation of Palestine. The aircraft was en route from Rome, Italy, to Lod, Israel.

1973    Varig Flight 820, operated by a Boeing 707 crashes near Paris on approach to Orly Airport, killing 123 of the 134 on-board.

1975    A privately chartered Boeing 707 crashes into the mountainside near Agadir, Morocco, killing 188.

1976    A Bolivian Boeing 707 cargo jet crashes in Santa Cruz, Bolivia, killing 100 (97, mostly children, killed on the ground).

1979    Varig 707-323C freighter, flown by the same commander as Flight 820, disappears over the Pacific Ocean 30 minutes after taking off from Tokyo.

1989    An Independent Air Boeing 707 crashes into Santa Maria mountain in Azores Islands off the coast of Portugal, killing 144.