Zinc finger protein 804A
Encyclopedia
Zinc finger protein 804A or ZNF804A is a human protein that has a zinc finger
in its structure.
. Later, the same SNP was reported to correlate with slightly disturbed functional coupling of several brain regions in healthy persons, according to authors, resembling the changes described in schizophrenia
.
Zinc finger
Zinc fingers are small protein structural motifs that can coordinate one or more zinc ions to help stabilize their folds. They can be classified into several different structural families and typically function as interaction modules that bind DNA, RNA, proteins, or small molecules...
in its structure.
Clinical significance
In a genome-wide study conducted in 2008, the rs1344706 SNP of the gene was shown to associate with schizophreniaSchizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...
. Later, the same SNP was reported to correlate with slightly disturbed functional coupling of several brain regions in healthy persons, according to authors, resembling the changes described in schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...
.