William Prusoff
Encyclopedia
William Herman Prusoff was a pharmacologist who was an early innovator in antiviral drugs, developing idoxuridine
, the first antiviral agent approved by the FDA
, in the 1950s, and co-developing (with Tai-shun Lin) stavudine
, one of the earliest AIDS
drugs, in the mid-1980s.
Idoxuridine
Idoxuridine is an anti-herpesvirus antiviral drug.It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to...
, the first antiviral agent approved by the FDA
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
, in the 1950s, and co-developing (with Tai-shun Lin) stavudine
Stavudine
Stavudine is a nucleoside analog reverse transcriptase inhibitor active against HIV.-History:...
, one of the earliest AIDS
AIDS
Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the human immunodeficiency virus...
drugs, in the mid-1980s.