Titan Pharmaceuticals
Encyclopedia
Titan Pharmaceuticals, Inc. is a California
California
California is a state located on the West Coast of the United States. It is by far the most populous U.S. state, and the third-largest by land area...

 biopharmaceutical company. Titan develops proprietary therapeutics for the treatment of central nervous system
Central nervous system
The central nervous system is the part of the nervous system that integrates the information that it receives from, and coordinates the activity of, all parts of the bodies of bilaterian animals—that is, all multicellular animals except sponges and radially symmetric animals such as jellyfish...

 disorders, cardiovascular disease
Cardiovascular disease
Heart disease or cardiovascular disease are the class of diseases that involve the heart or blood vessels . While the term technically refers to any disease that affects the cardiovascular system , it is usually used to refer to those related to atherosclerosis...

, bone disease
Bone disease
-Terminology:A bone disease is also called an "osteopathy", but because the term osteopathy is often used to a health-care approach, use of the term can cause some confusion.-Bone and cartilage disorders:...

, and other disorders primarily in the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

. Its products in development include probuphine, in Phase III clinical trials  for the treatment of opioid
Opioid
An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract...

 dependence; iloperidone
Iloperidone
Iloperidone, also known as Fanapt, Fanapta, and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia. It was approved by the U.S...

, has been approved by FDA for the treatment of schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...

 and related psychotic disorders; and spheramine, in Phase IIb for the treatment of advanced Parkinson's disease
Parkinson's disease
Parkinson's disease is a degenerative disorder of the central nervous system...

. The company’s potential products also include DITPA, in Phase II for the treatment of congestive heart failure and hyperlipidemia.

Titan has a strategic alliance with Schering AG for the development of spheramine and Vanda Pharmaceuticals, Inc. for the development of iloperidone. Titan Pharmaceuticals was founded by Louis R. Bucalo. The company was incorporated in 1992 and is based in South San Francisco, California.

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