Thomas Stephen Cullen
Encyclopedia
Dr. Thomas Stephen Cullen (1868–1953) was a canadian gynecologist
associated with Johns Hopkins Hospital
.
Born in Bridgewater, Ontario
, Cullen was educated at the Toronto Collegiate Institute and the University of Toronto
, graduating from the latter school with a Bachelor of Medicine degree in 1890. He began studying at Johns Hopkins University
the next year, before traveling to Germany
and studying at Johannes Orth
's laboratory at the University of Göttingen in 1893. From 1893 to 1896, Cullen was in charge of gynecological pathology
at Johns Hopkins, and in 1919 he was named a professor of clinical gynecology.
Cullen researched gynecological diseases including uterine cancer
and ectopic pregnancy
and promoted extensive use of diagrams in biomedical publishing. Cullen's sign
, a discoloration of the skin about the navel
which is regarded as a sign of a ruptured ectopic pregnancy, is named for him. He wrote alone, and in collaboration, four important monographs
:
Gynaecology
Gynaecology or gynecology is the medical practice dealing with the health of the female reproductive system . Literally, outside medicine, it means "the science of women"...
associated with Johns Hopkins Hospital
Johns Hopkins Hospital
The Johns Hopkins Hospital is the teaching hospital and biomedical research facility of Johns Hopkins University School of Medicine, located in Baltimore, Maryland . It was founded using money from a bequest by philanthropist Johns Hopkins...
.
Born in Bridgewater, Ontario
Ontario
Ontario is a province of Canada, located in east-central Canada. It is Canada's most populous province and second largest in total area. It is home to the nation's most populous city, Toronto, and the nation's capital, Ottawa....
, Cullen was educated at the Toronto Collegiate Institute and the University of Toronto
University of Toronto
The University of Toronto is a public research university in Toronto, Ontario, Canada, situated on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada...
, graduating from the latter school with a Bachelor of Medicine degree in 1890. He began studying at Johns Hopkins University
Johns Hopkins University
The Johns Hopkins University, commonly referred to as Johns Hopkins, JHU, or simply Hopkins, is a private research university based in Baltimore, Maryland, United States...
the next year, before traveling to Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...
and studying at Johannes Orth
Johannes Orth
Johannes Orth was a German pathologist who was a native of Wallmerod. He studied medicine at the University of Bonn, earning his doctorate in 1872. Afterwards he became an assistant to Rudolf Virchow in Berlin...
's laboratory at the University of Göttingen in 1893. From 1893 to 1896, Cullen was in charge of gynecological pathology
Pathology
Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....
at Johns Hopkins, and in 1919 he was named a professor of clinical gynecology.
Cullen researched gynecological diseases including uterine cancer
Uterine cancer
The term uterine cancer may refer to any of several different types of cancer which occur in the uterus, namely:*Uterine sarcomas: sarcomas of the myometrium, or muscular layer of the uterus, are most commonly leiomyosarcomas.*Endometrial cancer:...
and ectopic pregnancy
Ectopic pregnancy
An ectopic pregnancy, or eccysis , is a complication of pregnancy in which the embryo implants outside the uterine cavity. With rare exceptions, ectopic pregnancies are not viable. Furthermore, they are dangerous for the parent, since internal haemorrhage is a life threatening complication...
and promoted extensive use of diagrams in biomedical publishing. Cullen's sign
Cullen's sign
Cullen's sign is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus.It is named for Thomas S. Cullen , an obstetrician who first described the sign in ruptured ectopic pregnancy in 1916....
, a discoloration of the skin about the navel
Navel
The navel is a scar on the abdomen caused when the umbilical cord is removed from a newborn baby...
which is regarded as a sign of a ruptured ectopic pregnancy, is named for him. He wrote alone, and in collaboration, four important monographs
Book
A book is a set or collection of written, printed, illustrated, or blank sheets, made of hot lava, paper, parchment, or other materials, usually fastened together to hinge at one side. A single sheet within a book is called a leaf or leaflet, and each side of a leaf is called a page...
:
- Cancer of the UterusUterusThe uterus or womb is a major female hormone-responsive reproductive sex organ of most mammals including humans. One end, the cervix, opens into the vagina, while the other is connected to one or both fallopian tubes, depending on the species...
(1900) - Adenomyoma of the Uterus (1908)
- Myomata of the Uterus, with Howard Atwood KellyHoward Atwood KellyHoward Atwood Kelly was an American gynecologist. He was one of the "Big Four" founding professors at Johns Hopkins Hospital. Howard Atwood Kelly (February 20, 1858 – January 12, 1943) was an American gynecologist. He was one of the "Big Four" founding professors at Johns Hopkins Hospital....
(1909) - Diseases of the UmbilicusNavelThe navel is a scar on the abdomen caused when the umbilical cord is removed from a newborn baby...
(1916)