A thiazide-like diuretic is a sulfonamide

Sulfonamide (medicine)

Sulfonamide or sulphonamide is the basis of several groups of drugs. The original antibacterial sulfonamides are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of antibacterial activity, e.g., the anticonvulsant sultiame...

 diuretic

Diuretic

A diuretic provides a means of forced diuresis which elevates the rate of urination. There are several categories of diuretics. All diuretics increase the excretion of water from bodies, although each class does so in a distinct way.- Medical uses :...

 that has similar physiological properties to a thiazide

Thiazide

Thiazide is a term used to describe a type of molecule and a class of diuretics often used to treat hypertension and edema ....

 diuretic, but doesn't have the chemical properties of a thiazide, lacking the benzothiadiazine

Benzothiadiazine

Benzothiadiazine is a bicyclic heterocyclic benzene derivative with the heterocycle containing two nitrogens and one sulfur.Benzothiadiazine derivatives include:* bendroflumethiazide* chlorothiazide* cyclothiazide* hydrochlorothiazide* diazoxide...

 molecular structure.

Examples include chlorthalidone and metolazone

Metolazone

Metolazone is a thiazide-like diuretic marketed under the brand names Zytanix from Zydus Cadila, Zaroxolyn, and Mykrox. It is primarily used to treat congestive heart failure and high blood pressure. Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney,...

.

Some, such as indapamide

Indapamide

Indapamide is a thiazide diuretic drug marketed by Servier, generally used in the treatment of hypertension, as well as decompensated cardiac failure. The US trade name for indapamide is Lozol. Indapamide is marketed as Natrilix outside of the US, as Insig in Australia...

are considered thiazide-like diuretics, but don't necessarily have the same mechanism.