TDIQ
Encyclopedia
TDIQ is a drug used in scientific research, which has anxiolytic
and anorectic
effects in animals. It has an unusual effects profile in animals, with the effects generalising to cocaine
and partially to MDMA and ephedrine
, but the effects did not generalise to amphetamine
and TDIQ does not have any stimulant
effects. It is thought these effects are mediated via a partial agonist
action at Alpha-2 adrenergic receptor
s, and TDIQ has been suggested as a possible drug for the treatment of cocaine dependence.
Anxiolytic
An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...
and anorectic
Anorectic
An anorectic or anorexic , also known as anorexigenic or appetite suppressant, is a dietary supplement and/or drug which reduces appetite, food consumption, and as a result, causes weight loss to occur.-List of anorectics:Numerous pharmaceutical compounds are marketed as appetite suppressants.The...
effects in animals. It has an unusual effects profile in animals, with the effects generalising to cocaine
Cocaine
Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic...
and partially to MDMA and ephedrine
Ephedrine
Ephedrine is a sympathomimetic amine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia....
, but the effects did not generalise to amphetamine
Amphetamine
Amphetamine or amfetamine is a psychostimulant drug of the phenethylamine class which produces increased wakefulness and focus in association with decreased fatigue and appetite.Brand names of medications that contain, or metabolize into, amphetamine include Adderall, Dexedrine, Dextrostat,...
and TDIQ does not have any stimulant
Stimulant
Stimulants are psychoactive drugs which induce temporary improvements in either mental or physical function or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others...
effects. It is thought these effects are mediated via a partial agonist
Partial agonist
Partial agonists bind and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist...
action at Alpha-2 adrenergic receptor
Alpha-2 adrenergic receptor
The alpha-2 adrenergic receptor is a G protein-coupled receptor associated with the Gi heterotrimeric G-protein. It consists of three highly homologous subtypes, including α2A-, α2B-, and α2C-adrenergic. Some species other than humans express a fourth α2D-adrenergic receptor as well...
s, and TDIQ has been suggested as a possible drug for the treatment of cocaine dependence.
See also
- MDAI5,6-Methylenedioxy-2-aminoindane5,6-Methylenedioxy-2-aminoindane is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University. It acts as a non-neurotoxic and highly selective serotonin releasing agent in vitro and produces entactogen effects in humans.- Chemistry :The chemical structure of MDAI is...
- MDAT
- NorsalsolinolNorsalsolinolNorsalsolinol is a chemical compound that is produced naturally in the body through metabolism of dopamine. It has been shown to be a selective dopaminergic neurotoxin, and has been suggested as a possible cause of neurodegenerative conditions such as Parkinson's disease and the brain damage...
- TetrahydroisoquinolineTetrahydroisoquinolineTetrahydroisoquinoline is a secondary amine with the chemical formula C9H11N.-Reactions:Like other secondary amines, tetrahydroisoquinoline can be oxidized to the corresponding nitrone using hydrogen peroxide, catalyzed by selenium dioxide....