Synchysis scintillans
Encyclopedia
Synchysis scintillans is a degenerative condition of the eye
Eye
Eyes are organs that detect light and convert it into electro-chemical impulses in neurons. The simplest photoreceptors in conscious vision connect light to movement...

 seen uncommonly in dogs, resulting in liquified vitreous humor and the accumulation of cholesterol
Cholesterol
Cholesterol is a complex isoprenoid. Specifically, it is a waxy steroid of fat that is produced in the liver or intestines. It is used to produce hormones and cell membranes and is transported in the blood plasma of all mammals. It is an essential structural component of mammalian cell membranes...

 crystals within the vitreous. It is also known as cholesterosis bulbi. The vitreous liquifies in a process known as syneresis
Syneresis (chemistry)
Syneresis , in chemistry, is the extraction or expulsion of a liquid from a gel, as when lymph drains from a contracting clot of blood. Another example of syneresis is the collection of whey on the surface of yogurt...

. Synchysis scintillans appears as small white floater
Floater
Floaters are deposits of various size, shape, consistency, refractive index, and motility within the eye's vitreous humour, which is normally transparent. At young age the vitreous is perfectly transparent, but during life imperfections gradually develop. The common type of floater, which is...

s that freely move in the posterior part of the eye, giving a snow globe
Snow globe
A snow globe is a transparent sphere, usually made of glass, enclosing a miniaturized scene of some sort, often together with a model of a landscape. The sphere also encloses the water in the globe; the water serves as the medium through which the "snow" falls. To activate the snow, the globe is...

effect. It is most commonly seen in eyes that have suffered from a degenerative disease and are end-stage.
In humans as well, the condition is seen rarely. Associated with the advanced stages of diabetic retinopathy, but the exact pathogenesis is unknown.
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