Suppressor mutation
Encyclopedia
A suppressor mutation is a mutation
that counteracts the phenotypic
effects of another mutation.
There are several classes
Mutation
In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic...
that counteracts the phenotypic
Phenotype
A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior...
effects of another mutation.
There are several classes
- mutation within the same gene
- e.g. second frameshift that occurs near the first one
- mutation within another gene (extragenic mutation)
- that restore the function of the original mutated gene
- that results in the production of a protein that replaces the mutated one
- intergenic mutation.