Spin probe
Encyclopedia
A spin probe is a molecule
with stable free radical character that carries a functional group
. This group can be used to couple the probe to another molecule, e.g. a biomolecule
.
Electron spin resonance can be employed to quantify the probe's concentration.
See also: Spin label
Molecule
A molecule is an electrically neutral group of at least two atoms held together by covalent chemical bonds. Molecules are distinguished from ions by their electrical charge...
with stable free radical character that carries a functional group
Functional group
In organic chemistry, functional groups are specific groups of atoms within molecules that are responsible for the characteristic chemical reactions of those molecules. The same functional group will undergo the same or similar chemical reaction regardless of the size of the molecule it is a part of...
. This group can be used to couple the probe to another molecule, e.g. a biomolecule
Biomolecule
A biomolecule is any molecule that is produced by a living organism, including large polymeric molecules such as proteins, polysaccharides, lipids, and nucleic acids as well as small molecules such as primary metabolites, secondary metabolites, and natural products...
.
Electron spin resonance can be employed to quantify the probe's concentration.
See also: Spin label
Spin label
A spin label is an organic molecule which possesses an unpaired electron, usually on a nitrogen atom, and the ability to bind to another molecule. Spin labels are normally used as tools for probing proteins or biological membrane-local dynamics using EPR spectroscopy. The site-directed spin...