Sophia Frangou
Encyclopedia
Sophia Frangou is Reader in Psychiatry at the Institute of Psychiatry, King's College London
Institute of Psychiatry
The Institute of Psychiatry is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways to prevent them in the first place...

 where she heads the Neurobiology of Psychosis section. She is a Fellow of the Royal College of Psychiatrists
Royal College of Psychiatrists
The Royal College of Psychiatrists is the main professional organisation of psychiatrists in the United Kingdom responsible for representing psychiatrists, psychiatric research and providing public information about mental health problems...

 and of the European Psychiatric Association (EPA) and Vice-President for Research of the International Society for Bipolar Disorders
International Society for Bipolar Disorders
The International Society for Bipolar Disorders is a non-profit organization based in Pittsburgh, Pennsylvania, USA, where it was founded June 17, 1999 . The society focuses on research and education in bipolar disorders....

. She is secretary and founding member of the EPA NeuroImaging section and heads the Brain Imaging Network of the European College of Neuropsychopharmacology. She is one of the three Editors of European Psychiatry
European Psychiatry
European Psychiatry is the official journal of the European Psychiatric Association. It covers topics on psychopathology, nosography, chemotherapy, psychotherapy, clinical methodology, biological disorders and mental pathology, psychophysiology, neuropsychology, as well as animal behavior.-...

, the official Journal of the European Psychiatric Association. She has also served on the Council of the British Association for Psychopharmacology.

Biography

Frangou graduated from the Medical School of the University of Athens, Greece in 1989. She then moved to the UK where she trained in psychiatry at the Maudsley Hospital
Maudsley Hospital
The Maudsley Hospital is a British psychiatric hospital in South London. The Maudsley is the largest mental health training institution in the country...

, London. She obtained her Masters Degree in Neuroscience from the University of London, UK and trained in the US as a research fellow at the Department of Psychiatry and Behavioural Sciences at the Johns Hopkins University She returned to the Institute of Psychiatry
Institute of Psychiatry
The Institute of Psychiatry is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways to prevent them in the first place...

, King's College London where she completed her PhD on neuroimaging
Neuroimaging
Neuroimaging includes the use of various techniques to either directly or indirectly image the structure, function/pharmacology of the brain...

 and electrophysiological
Event-related potential
An event-related potential is any measured brain response that is directly the result of a thought or perception. More formally, it is any stereotyped electrophysiological response to an internal or external stimulus....

 markers of familial vulnerability to schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...

. She works as a Consultant Psychiatrist at the Maudsley Hospital and leads her own research group at the Institute of Psychiatry, King's College London.

Research

Frangou's research focuses on the pathophysiological processes underlying psychosis, with emphasis on schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...

 and bipolar disorder
Bipolar disorder
Bipolar disorder or bipolar affective disorder, historically known as manic–depressive disorder, is a psychiatric diagnosis that describes a category of mood disorders defined by the presence of one or more episodes of abnormally elevated energy levels, cognition, and mood with or without one or...

 using clinical, genetic, cognitive and neuroimaging
Neuroimaging
Neuroimaging includes the use of various techniques to either directly or indirectly image the structure, function/pharmacology of the brain...

 techniques. Her key contributions in the field relate to the neurobiological correlates that influence the age when psychosis becomes clinical apparent and on the functional impact of susceptibility genes for schizophrenia and bipolar disorder on brain structure and function. More recently her work is focused on the examination of biological processes that determine resilience to mental illness and differentiate bipolar disorder from schizophrenia.

In parallel Frangou is also interested in the standardisation of cognitive test batteries for the assessment of cognition in psychosis as a means to facilitating large scale international collaborative research such as the ISBD neurocognition initiative ISBD-BANC.

Recent publications

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See also

  • Institute of Psychiatry
    Institute of Psychiatry
    The Institute of Psychiatry is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways to prevent them in the first place...

  • Maudsley Hospital
    Maudsley Hospital
    The Maudsley Hospital is a British psychiatric hospital in South London. The Maudsley is the largest mental health training institution in the country...

  • International Society for Bipolar Disorders
    International Society for Bipolar Disorders
    The International Society for Bipolar Disorders is a non-profit organization based in Pittsburgh, Pennsylvania, USA, where it was founded June 17, 1999 . The society focuses on research and education in bipolar disorders....

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