Sodium aurothiomalate
Encyclopedia
Sodium aurothiomalate (gold sodium thiomalate) is a gold compound with the chemical formula C4H4Au
Na
O4S and is used for its antirheumatic
effects to treat rheumatoid arthritis
. In the United Kingdom only the intramuscular injection drug Myocrisin (which contains a mixture of sodium aurothiomalate and disodium aurothiomalate
) and the orally taken Auranofin
are used medically.
Gold
Gold is a chemical element with the symbol Au and an atomic number of 79. Gold is a dense, soft, shiny, malleable and ductile metal. Pure gold has a bright yellow color and luster traditionally considered attractive, which it maintains without oxidizing in air or water. Chemically, gold is a...
Na
Sodium
Sodium is a chemical element with the symbol Na and atomic number 11. It is a soft, silvery-white, highly reactive metal and is a member of the alkali metals; its only stable isotope is 23Na. It is an abundant element that exists in numerous minerals, most commonly as sodium chloride...
O4S and is used for its antirheumatic
Disease-modifying antirheumatic drug
Disease-modifying antirheumatic drugs is a category of otherwise unrelated drugs defined by their use in rheumatoid arthritis to slow down disease progression...
effects to treat rheumatoid arthritis
Rheumatoid arthritis
Rheumatoid arthritis is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The process produces an inflammatory response of the synovium secondary to hyperplasia of synovial cells, excess synovial fluid, and the development...
. In the United Kingdom only the intramuscular injection drug Myocrisin (which contains a mixture of sodium aurothiomalate and disodium aurothiomalate
Disodium aurothiomalate
Disodium aurothiomalate is a chemical compound with the formula AuSCHCH2CO2Na. In conjunction with its monoprotonated derivative, this coordination complex or closely related species are used to treat rheumatoid arthritis, under the tradename Myochrysine. The thiomalate is racemic in most...
) and the orally taken Auranofin
Auranofin
Auranofin is a gold complex classified by the World Health Organization as an antirheumatic agent.It has the brand name Ridaura.-Use in HIV infection:...
are used medically.
See also
- AuranofinAuranofinAuranofin is a gold complex classified by the World Health Organization as an antirheumatic agent.It has the brand name Ridaura.-Use in HIV infection:...
- AurothioglucoseAurothioglucoseAurothioglucose, also known as gold thioglucose, is a chemical compound with the formula AuSC6H11O5. This derivative of the sugar glucose is used to treat rheumatoid arthritis.-History:...
- Disodium aurothiomalateDisodium aurothiomalateDisodium aurothiomalate is a chemical compound with the formula AuSCHCH2CO2Na. In conjunction with its monoprotonated derivative, this coordination complex or closely related species are used to treat rheumatoid arthritis, under the tradename Myochrysine. The thiomalate is racemic in most...
- Gold saltsGold saltsGold salts describe ionic chemical compounds of gold. The term, which is a misnomer, has evolved into a synonym for the gold compounds used in medicine...