Smad proteins, inhibitory
Encyclopedia
I-SMAD or Inhibitor SMAD is a subclass of SMAD
s that are involved in the modulation of transforming growth factor beta ligands. This class includes SMAD6
and SMAD7
. They compete with SMAD4
and consequently regulate the transcription of its gene products.
SMAD (protein)
SMADs are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream TGF-β gene transcription....
s that are involved in the modulation of transforming growth factor beta ligands. This class includes SMAD6
Mothers against decapentaplegic homolog 6
SMAD family member 6, also known as SMAD6, is a protein that in humans is encoded by the SMAD6 gene.SMAD6 is a protein that, as its name describes, is a homolog of the Drosophila gene "mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGFβ superfamily...
and SMAD7
Mothers against decapentaplegic homolog 7
Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene.SMAD7 is a protein that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGFβ...
. They compete with SMAD4
Mothers against decapentaplegic homolog 5
Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SAMD5 gene.SMAD5, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGFβ...
and consequently regulate the transcription of its gene products.