Raf-like Ras-binding domain
Encyclopedia
Raf-like Ras-binding domain is an evolutionary conserved protein domain
. This is the Ras-binding domain found in proteins related to Ras.
Protein domain
A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural...
. This is the Ras-binding domain found in proteins related to Ras.
Examples
Human proteins containing this domain include:- ARAFARAFSerine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ARAF gene. A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases.-Interactions:...
- BRAFBRAF (gene)Serine/threonine-protein kinase B-Raf or simply B-Raf, also known as proto-oncogene B-Raf or v-Raf murine sarcoma viral oncogene homolog B1, is a protein that in humans is encoded by the BRAF gene...
- RAF1C-RafRAF proto-oncogene serine/threonine-protein kinase also known as proto-oncogene c-RAF or simply c-Raf is an enzyme that in humans is encoded by the RAF1 gene. The c-Raf protein functions in the MAPK/ERK signal transduction pathway as part of a protein kinase cascade...
- RGS12RGS12Regulator of G-protein signaling 12 is a protein that in humans is encoded by the RGS12 gene.-Interactions:RGS12 has been shown to interact with GNAI1 and GNAI3.-Further reading:...
, RGS14RGS14Regulator of G-protein signaling 14 is a protein that in humans is encoded by the RGS14 gene.- Function :RGS14 is a member of the regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains , and one GoLoco motif... - TIAM1T-cell lymphoma invasion and metastasis-inducing protein 1T-cell lymphoma invasion and metastasis-inducing protein 1 is a protein that in humans is encoded by the TIAM1 gene.- Structure :TIAM1 is tightly associate with BAIAP2 as a subunit...