Pseudotyped virus
Encyclopedia
A pseudotyped virus is an enveloped virus
particle assembled with a foreign viral glycoprotein
. The process of producing such particles is termed pseudotyping
.
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...
particle assembled with a foreign viral glycoprotein
Glycoprotein
Glycoproteins are proteins that contain oligosaccharide chains covalently attached to polypeptide side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycosylation. In proteins that have segments extending...
. The process of producing such particles is termed pseudotyping
Pseudotyping
Pseudotyping is the process of producing viruses or viral vectors in combination with foreign viral envelope proteins. The result is a pseudotyped virus particle.. With this method, the foreign viral envelope proteins can be used to alter host tropism or an increased/decreased stability of the...
.