Prostaglandin H2
Encyclopedia
Prostaglandin H2 is a type of Prostaglandin
which is derived from arachidonic acid
and is a precursor for many other biologically significant molecules.
It is acted upon by:
Prostaglandin
A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring....
which is derived from arachidonic acid
Arachidonic acid
Arachidonic acid is a polyunsaturated omega-6 fatty acid 20:4.It is the counterpart to the saturated arachidic acid found in peanut oil, Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).It is the counterpart to the saturated arachidic acid found in peanut oil,...
and is a precursor for many other biologically significant molecules.
- prostacyclin synthaseProstacyclin synthaseProstaglandin-I synthase also known as prostaglandin I2 synthase or CYP8A1 is an enzyme involved in prostanoid biosynthesis that in humans is encoded by the PTGIS gene. This enzyme belongs to the family of cytochrome P450 isomerases.- Function :This gene encodes a member of the cytochrome P450...
to create prostacyclinProstacyclinProstacyclin is a member of the family of lipid molecules known as eicosanoids.As a drug, it is also known as "epoprostenol". The terms are sometimes used interchangeably.-History:... - thromboxane-A synthaseThromboxane-A synthaseThromboxane A synthase 1 , also known as TBXAS1, is an enzyme that, in humans, is encoded by the TBXAS1 gene.- Function :This gene encodes a member of the cytochrome P450 superfamily of enzymes...
to create thromboxane A2Thromboxane A2Thromboxane A2 is a thromboxane. It is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. This is achieved by mediating expression of the glycoprotein complex GP IIb/IIIa in the cell membrane of... - prostaglandin D2 synthaseProstaglandin D2 synthaseProstaglandin-H2 D-isomerase is an enzyme that in humans is encoded by the PTGDS gene.-Further reading:...
to create prostaglandin D2Prostaglandin D2Prostaglandin D2 is a prostaglandin that binds to the receptor PTGDR, as well as CRTH2. It is a major prostaglandin produced by mast cells – recruits Th2 cells, eosinophils, basophils. In mammalian organs, large amounts of PGD2 are found in the brain, in mast cells and found nowhere else... - Prostaglandin E synthaseProstaglandin E synthaseProstaglandin E synthase is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E from prostaglandin H2.The synthase generating PGE2 is a membrane-associated protein....
to create prostaglandin E2