Prostaglandin E
Encyclopedia
Prostaglandin E is a family of naturally occurring prostaglandin
Prostaglandin
A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring....

s and may be used pharmaceutically in medicine.

Types include:
  • Prostaglandin E1
    Prostaglandin E1
    Prostaglandin E1 , known pharmaceutically as alprostadil, is a prostaglandin. It is a drug used in the treatment of erectile dysfunction and has vasodilatory properties.-Sexual dysfunction:...

     also termed Alprostadil
  • Prostaglandin E2 also termed Dinoprostone


It is created from prostaglandin E synthase
Prostaglandin E synthase
Prostaglandin E synthase is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E from prostaglandin H2.The synthase generating PGE2 is a membrane-associated protein....

.

Prostaglandin E2

Prostaglandin E2 is secreted in microvessels by the endothelium. It is a direct vasodilator and it inhibits the release of noradrenaline from sympathetic nerve terminals. It doesn't have the effect on platelets PGI2 does.
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