Pristane
Encyclopedia
Pristane is a natural saturated
terpenoid
alkane
obtained primarily from shark liver oil
, from which its name is derived (Latin
pristis, "shark"). It is also found in mineral oil and some foods. It is a transparent oily liquid that is immiscible
with water, but soluble in diethyl ether
, benzene
, chloroform
and carbon tetrachloride
.
Pristane is known to induce autoimmune diseases in rodents. It is used in research to understand the pathogenesis of rheumatoid arthritis and lupus. The fact that it is used in many products, raises the possibility that it may be a possible environmental exposure that may trigger diseases such as lupus and rheumatoid arthritis.
It is used as a lubricant, a transformer oil, an immunologic adjuvant
, and an anti-corrosion agent, biological marker, plasmocytomas inducer and in production of monoclonal antibodies.
Biosynthetically, pristane is derived from phytol
. Often used as a biomarker in petroleum studies.
Saturation (chemistry)
In chemistry, saturation has six different meanings, all based on reaching a maximum capacity...
terpenoid
Terpenoid
The terpenoids , sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals similar to terpenes, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in...
alkane
Alkane
Alkanes are chemical compounds that consist only of hydrogen and carbon atoms and are bonded exclusively by single bonds without any cycles...
obtained primarily from shark liver oil
Shark liver oil
Shark liver oil is obtained from sharks that are caught for food purposes and are living in cold, deep oceans. The liver oil from sharks has been used by fishermen for centuries as a folk remedy for general health...
, from which its name is derived (Latin
Latin
Latin is an Italic language originally spoken in Latium and Ancient Rome. It, along with most European languages, is a descendant of the ancient Proto-Indo-European language. Although it is considered a dead language, a number of scholars and members of the Christian clergy speak it fluently, and...
pristis, "shark"). It is also found in mineral oil and some foods. It is a transparent oily liquid that is immiscible
Miscibility
Miscibility is the property of liquids to mix in all proportions, forming a homogeneous solution. In principle, the term applies also to other phases , but the main focus is usually on the solubility of one liquid in another...
with water, but soluble in diethyl ether
Diethyl ether
Diethyl ether, also known as ethyl ether, simply ether, or ethoxyethane, is an organic compound in the ether class with the formula . It is a colorless, highly volatile flammable liquid with a characteristic odor...
, benzene
Benzene
Benzene is an organic chemical compound. It is composed of 6 carbon atoms in a ring, with 1 hydrogen atom attached to each carbon atom, with the molecular formula C6H6....
, chloroform
Chloroform
Chloroform is an organic compound with formula CHCl3. It is one of the four chloromethanes. The colorless, sweet-smelling, dense liquid is a trihalomethane, and is considered somewhat hazardous...
and carbon tetrachloride
Carbon tetrachloride
Carbon tetrachloride, also known by many other names is the organic compound with the formula CCl4. It was formerly widely used in fire extinguishers, as a precursor to refrigerants, and as a cleaning agent...
.
Pristane is known to induce autoimmune diseases in rodents. It is used in research to understand the pathogenesis of rheumatoid arthritis and lupus. The fact that it is used in many products, raises the possibility that it may be a possible environmental exposure that may trigger diseases such as lupus and rheumatoid arthritis.
It is used as a lubricant, a transformer oil, an immunologic adjuvant
Immunologic adjuvant
In immunology, an adjuvant is an agent that may stimulate the immune system and increase the response to a vaccine, without having any specific antigenic effect in itself. The word “adjuvant” comes from the Latin word adiuvare, meaning to help or aid...
, and an anti-corrosion agent, biological marker, plasmocytomas inducer and in production of monoclonal antibodies.
Biosynthetically, pristane is derived from phytol
Phytol
Phytol is an acyclic diterpene alcohol that can be used as a precursor for the manufacture of synthetic forms of vitamin E and vitamin K1. In ruminants, the gut fermentation of ingested plant materials liberates phytol, a constituent of chlorophyll, which is then converted to phytanic acid and...
. Often used as a biomarker in petroleum studies.