Pregnancy rate
Encyclopedia
Pregnancy rate in infertility treatment is the success rate
for pregnancy
. It is the percentage of all attempts that leads to pregnancy, with attempts generally referring to menstrual cycles where insemination
or any artificial equivalent is used, which may be simple artificial insemination
(AI) or AI with additional in vitro fertilization.
was performed. In terms of outcome, "pregnancy" may refer to a positive pregnancy test
, evidence of a pregnancy with a "viable" fetus or implantation (preferably specified as implantation rate). Furthermore, pregnancy rates can be influenced in IVF by transferring multiple embryos that may result in multiple birth
s. A strict definition in the IVF setting would refer to the singleton pregnancy rate that determines how many live singletons are born in relation to initiated IVF cycles.
s and stillbirth
s.
For instance, in 2007, Canadian clinics reported a live birth rate of 27% with in vitro fertilisation
.
treatment may be useful or necessary in couples with total fertilization failure.
using ICI, and and 15-20% per cycle for IUI.
Success rate
Success rate is the fraction or percentage of success among a number of attempts, and may refer to:* Opportunity success rate* When success refers to attempts to induce pregnancy, then pregnancy rate is used**Artificial insemination success rates...
for pregnancy
Pregnancy
Pregnancy refers to the fertilization and development of one or more offspring, known as a fetus or embryo, in a woman's uterus. In a pregnancy, there can be multiple gestations, as in the case of twins or triplets...
. It is the percentage of all attempts that leads to pregnancy, with attempts generally referring to menstrual cycles where insemination
Insemination
Insemination is the deliberate introduction of sperm into the uterus of a mammal or the oviduct of an oviparous animal for the objective of impregnating a female for reproduction...
or any artificial equivalent is used, which may be simple artificial insemination
Artificial insemination
Artificial insemination, or AI, is the process by which sperm is placed into the reproductive tract of a female for the purpose of impregnating the female by using means other than sexual intercourse or natural insemination...
(AI) or AI with additional in vitro fertilization.
Definitions
There is no universally accepted definition of the term. Thus in IVF pregnancy rates may be based on initiated treatment cycles, cycles that underwent oocyte retrieval, or cycles where an embryo transferEmbryo transfer
Embryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy...
was performed. In terms of outcome, "pregnancy" may refer to a positive pregnancy test
Pregnancy test
A pregnancy test attempts to determine whether or not a woman is pregnant.These markers are found in urine and blood, and pregnancy tests require sampling one of these substances. The first of these markers to be discovered, human chorionic gonadotropin , was discovered in 1930 to be produced by...
, evidence of a pregnancy with a "viable" fetus or implantation (preferably specified as implantation rate). Furthermore, pregnancy rates can be influenced in IVF by transferring multiple embryos that may result in multiple birth
Multiple birth
A multiple birth occurs when more than one fetus is carried to term in a single pregnancy. Different names for multiple births are used, depending on the number of offspring. Common multiples are two and three, known as twins and triplets...
s. A strict definition in the IVF setting would refer to the singleton pregnancy rate that determines how many live singletons are born in relation to initiated IVF cycles.
Related end-points
In some cases, success rates include delivery or presence of a live baby (preferably specified as delivery rate or live birth rate respectively).Live birth rate
Live birth rate is the percentage of all cycles that lead to live birth, and is the pregnancy rate adjusted for miscarriageMiscarriage
Miscarriage or spontaneous abortion is the spontaneous end of a pregnancy at a stage where the embryo or fetus is incapable of surviving independently, generally defined in humans at prior to 20 weeks of gestation...
s and stillbirth
Stillbirth
A stillbirth occurs when a fetus has died in the uterus. The Australian definition specifies that fetal death is termed a stillbirth after 20 weeks gestation or the fetus weighs more than . Once the fetus has died the mother still has contractions and remains undelivered. The term is often used in...
s.
For instance, in 2007, Canadian clinics reported a live birth rate of 27% with in vitro fertilisation
In vitro fertilisation
In vitro fertilisation is a process by which egg cells are fertilised by sperm outside the body: in vitro. IVF is a major treatment in infertility when other methods of assisted reproductive technology have failed...
.
Fertilization rate
In IVF or its derivatives, fertilization rate may be used to measure how many oocytes become fertilized by sperm cells. A fertilization rate of zero in one cycle, where no oocytes become fertilized, is termed a total fertilization failure. Repeated ICSIIntracytoplasmic sperm injection
Intracytoplasmic sperm injection is an in vitro fertilization procedure in which a single sperm is injected directly into an egg.-Indications:...
treatment may be useful or necessary in couples with total fertilization failure.
Pregnancy rate for AI
Generally, pregnancy rate for AI it is 10 to 15% per menstrual cycleMenstrual cycle
The menstrual cycle is the scientific term for the physiological changes that can occur in fertile women for the purpose of sexual reproduction. This article focuses on the human menstrual cycle....
using ICI, and and 15-20% per cycle for IUI.