Ponazuril sold by the Bayer Corporation
Bayer AG is a chemical and pharmaceutical company founded in Barmen , Germany in 1863. It is headquartered in Leverkusen, North Rhine-Westphalia, Germany and well known for its original brand of aspirin.-History:...

 under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis
Equine Protozoal Myeloencephalitis
Equine protozoal myeloencephalitis, or EPM, is a disease cause by a protozoal infection of the central nervous system of horses.-History:...

 in horses, caused by Sarcocystis
Sarcocystis is a genus of protozoa. Species in this genus infect reptiles, birds and mammals. The name is dervived from Greek: sarx = flesh and kystis = bladder.There are about 130 recognised species in this genus...

. More recently, veterinarians have been preparing a formulary version of the medication for use in small animals such as cats and dogs against coccidia, an intestinal parasite. Coccidia treatment is far shorter than treatment for EPM.
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