Pipermethystine
Encyclopedia
Pipermethystine is an alkaloid
Alkaloid
Alkaloids are a group of naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids...

 present in the aerial (aboveground) portions of the kava
Kava
Kava or kava-kava is a crop of the western Pacific....

plant.

Toxicity

Pipermethystine is known to induce hepatoxicity in humans, and is believed to be the cause of liver failure in individuals consuming kava supplements.
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