
Paternity testing
    
    Overview
    
        Parental testing is the use of genetic fingerprinting
to determine whether two individuals have a biological parent-child relationship. A paternity test establishes genetic proof as to whether a man is the biological father of an individual, and a maternity test establishes whether a woman is the biological mother of an individual. Though genetic testing is the most reliable standard, older methods also exist, including ABO blood group typing
, analysis of various other protein
s and enzyme
s, or using human leukocyte antigen
antigen
s.
Genetic fingerprinting
DNA profiling  is a technique employed by forensic scientists to assist in the identification of individuals  by their respective DNA profiles. DNA profiles are encrypted sets of numbers that reflect a person's DNA makeup, which can also be used as the person's identifier...
to determine whether two individuals have a biological parent-child relationship. A paternity test establishes genetic proof as to whether a man is the biological father of an individual, and a maternity test establishes whether a woman is the biological mother of an individual. Though genetic testing is the most reliable standard, older methods also exist, including ABO blood group typing
Blood type
A blood type  is a classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells . These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system...
, analysis of various other protein
Protein
Proteins  are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function.   A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
s and enzyme
Enzyme
Enzymes  are proteins that catalyze  chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
s, or using human leukocyte antigen
Human leukocyte antigen
The human leukocyte antigen  system  is the name of the major histocompatibility complex  in humans. The super locus contains a large number of genes related to immune system function in humans.  This group of genes resides on  chromosome 6, and encodes cell-surface antigen-presenting proteins and...
antigen
Antigen
An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then kill or neutralize the antigen that is recognized as a foreign and potentially harmful invader. These invaders can be molecules such as...
s.
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