Org 20599
Encyclopedia
Org 20599 is a synthetic neuroactive steroid
, with sedative
effects resulting from its action as a GABAA receptor positive modulator. It was developed for use as an anaesthetic agent but was never marketed for this purpose, although it is still used in scientific research.
Neuroactive steroid
Neuroactive steroids rapidly alter neuronal excitability through interaction with neurotransmitter-gated ion channels. In addition, these steroids may also exert effects on gene expression via intracellular steroid hormone receptors...
, with sedative
Sedative
A sedative or tranquilizer is a substance that induces sedation by reducing irritability or excitement....
effects resulting from its action as a GABAA receptor positive modulator. It was developed for use as an anaesthetic agent but was never marketed for this purpose, although it is still used in scientific research.