North Florida refers to the northernmost part of the U.S. state

U.S. state

A U.S. state is any one of the 50 federated states of the United States of America that share sovereignty with the federal government. Because of this shared sovereignty, an American is a citizen both of the federal entity and of his or her state of domicile. Four states use the official title of...

 of Florida

Florida

Florida is a state in the southeastern United States, located on the nation's Atlantic and Gulf coasts. It is bordered to the west by the Gulf of Mexico, to the north by Alabama and Georgia and to the east by the Atlantic Ocean. With a population of 18,801,310 as measured by the 2010 census, it...

, including some counties that border the state of Georgia

Georgia (U.S. state)

Georgia is a state located in the southeastern United States. It was established in 1732, the last of the original Thirteen Colonies. The state is named after King George II of Great Britain. Georgia was the fourth state to ratify the United States Constitution, on January 2, 1788...

. It also borders the Big Bend

Big Bend (Florida)

The Big Bend of Florida, U.S.A., is an informal region of the state with no official surveyed boundary. It includes part of the counties of the Florida Panhandle. Geologists prefer to characterize Florida’s Big Bend as the drowned karst section of the coast that occurs between the mouth of the...

 with Madison County

Madison County, Florida

Madison County is a county located in the state of Florida. As of 2000, the population was 18,733. The U.S. Census Bureau 2005 estimate for the county is 19,902. Its county seat is Madison, Florida. Madison County is one of Florida's five dry counties....

 and Taylor County

Taylor County, Florida

Taylor County is a county located in the state of Florida. As of 2000, the population was 19,256. The U.S. Census Bureau 2005 estimate for the county was 19,622 . Its county seat is Perry, Florida.- History :Taylor County was created in 1856...

 to the east and the Central Florida region to its south.

It is differentiated from the Florida Panhandle

Florida Panhandle

The Florida Panhandle, an informal, unofficial term for the northwestern part of Florida, is a strip of land roughly 200 miles long and 50 to 100 miles wide , lying between Alabama on the north and the west, Georgia also on the north, and the Gulf of Mexico to the south. Its eastern boundary is...

, Central Florida

Central Florida

Central Florida is a regional designation for the area surrounding Orlando in east central Florida, United States. The area represents the third largest population concentration in Florida, after the South Florida and Tampa Bay regions, respectively....

 and South Florida by the State of Florida. Its principal city is Jacksonville

Jacksonville, Florida

Jacksonville is the largest city in the U.S. state of Florida in terms of both population and land area, and the largest city by area in the contiguous United States. It is the county seat of Duval County, with which the city government consolidated in 1968...

 on the Atlantic.

The First Coast

First Coast

The First Coast is a region of Florida, in the United States. It extends along the Atlantic, or eastern, coast of the state, from the Georgia border, past the southern end of Anastasia Island, to Marineland....

region around Jacksonville is a sub region of North Florida.