Neurotmesis
Encyclopedia
Neurotmesis is part of Seddon's classification scheme used to classify nerve
Nerve
A peripheral nerve, or simply nerve, is an enclosed, cable-like bundle of peripheral axons . A nerve provides a common pathway for the electrochemical nerve impulses that are transmitted along each of the axons. Nerves are found only in the peripheral nervous system...

 damage.
It is the most serious nerve injury
Injury
-By cause:*Traumatic injury, a body wound or shock produced by sudden physical injury, as from violence or accident*Other injuries from external physical causes, such as radiation injury, burn injury or frostbite*Injury from infection...

 in the scheme.
In this type of injury, both the nerve
Nerve
A peripheral nerve, or simply nerve, is an enclosed, cable-like bundle of peripheral axons . A nerve provides a common pathway for the electrochemical nerve impulses that are transmitted along each of the axons. Nerves are found only in the peripheral nervous system...

 and the nerve sheath are disrupted.
While partial recovery may occur, complete recovery is impossible.

See also

  • Neurapraxia
    Neurapraxia
    Neurapraxia is a disorder of the peripheral nervous system in which there is a temporary loss of motor and sensory function due to blockage of nerve conduction, usually lasting an average of six to eight weeks before full recovery...

  • Axonotmesis
    Axonotmesis
    Axonotmesis is a disruption of nerve cell axon, with Wallerian degeneration occurring below and slightly proximal to the site of injury. If axons, and their myelin sheath are damaged, but schwann cells, the endoneurium, perineurium and epineurium remain intact is called axonotmesis. Axonotmesis is...

  • Nerve injury
    Nerve injury
    Nerve injury is injury to nervous tissue. There is no single classification system that can describe all the many variations of nerve injury. Most systems attempt to correlate the degree of injury with symptoms, pathology and prognosis...

  • Peripheral nerve injury
    Peripheral nerve injury
    Peripheral nerve damage is categorized in the Seddon classification based on the extent of damage to both the nerve and the surrounding connective tissue since the nervous system is characterized by dependence of neurons on their supporting glia. Unlike in the central nervous system, regeneration...

  • Neuroregeneration
  • Wallerian degeneration
    Wallerian degeneration
    Wallerian degeneration is a process that results when a nerve fiber is cut or crushed, in which the part of the axon separated from the neuron's cell body degenerates distal to the injury. This is also known as anterograde degeneration, or orthograde degeneration...

  • Seddon's classification
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