NFKB2
Encyclopedia
Nuclear factor NF-kappa-B p100 subunit is a protein
that in humans is encoded by the NFKB2 gene
.
with NFKBIE
, BCL3
, MAP3K8
, BTRC
, RELA
, RELB
, NFKB1
, REL
and TSC22D3
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the NFKB2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
NFKB2 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with NFKBIE
NFKBIE
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene.- Function :...
, BCL3
BCL3
B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene.This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin...
, MAP3K8
MAP3K8
Mitogen-activated protein kinase 8 is an enzyme that in humans is encoded by the MAP3K8 gene.-Interactions:MAP3K8 has been shown to interact with AKT1, CHUK, NFKB2 and NFKB1.-Further reading:...
, BTRC
BTRC (gene)
F-box/WD repeat-containing protein 1A also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC gene....
, RELA
RELA
Transcription factor p65 is a protein that in humans is encoded by the RELA gene.-Interactions:RELA has been shown to interact with NFKBIB, ETHE1, NFKBIE, RFC1, TRIB3, CREB binding protein, Neutrophil cytosolic factor 1, Glucocorticoid receptor, MTPN, BRCA1, C-Fos, POU2F1, BTRC, TATA-binding...
, RELB
RELB
Transcription factor RelB is a protein that in humans is encoded by the RELB gene.-Interactions:RELB has been shown to interact with NFKB2 and NFKB1.-References:...
, NFKB1
NFKB1
Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene.This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and...
, REL
REL
The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. The c-Rel protein is a member of the NF-κB family of transcription factors and contains a Rel homology domain at its N-terminus and two C-terminal transactivation domains. c-Rel has an important role in B-cell...
and TSC22D3
TSC22D3
TSC22 domain family protein 3 is a protein that in humans is encoded by the TSC22D3 gene.-Interactions:TSC22D3 has been shown to interact with C-Raf, NFKB2 and NFKB1.-Further reading:...
.