Melvin H. Knisely
Encyclopedia
Melvin Henry Knisely was an American
physiologist who first observed the pathological clumping of red
and white cells
, in vivo, at the capillary
level. One of the most cited Knisely works was his research which documented the fact that even one drink kills brain cells, which are irreplaceable.
In 1948, Knisely was nominated for a Nobel Prize
by his mentor August Krogh
, the 1920 Nobel Laureate winner for physiology and medicine.
Knisely's positions included a term as chairman of the Department of Anatomy at the Medical College of South Carolina (1948–1974).
In 1983 The International Society on Oxygen Transport to Tissue
established the Melvin H. Knisely Award to honor Knisely’s accomplishments in the field of the transport of oxygen and other metabolites
and anabolites
in the human body.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
physiologist who first observed the pathological clumping of red
Red blood cell
Red blood cells are the most common type of blood cell and the vertebrate organism's principal means of delivering oxygen to the body tissues via the blood flow through the circulatory system...
and white cells
White blood cell
White blood cells, or leukocytes , are cells of the immune system involved in defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a...
, in vivo, at the capillary
Capillary
Capillaries are the smallest of a body's blood vessels and are parts of the microcirculation. They are only 1 cell thick. These microvessels, measuring 5-10 μm in diameter, connect arterioles and venules, and enable the exchange of water, oxygen, carbon dioxide, and many other nutrient and waste...
level. One of the most cited Knisely works was his research which documented the fact that even one drink kills brain cells, which are irreplaceable.
In 1948, Knisely was nominated for a Nobel Prize
Nobel Prize
The Nobel Prizes are annual international awards bestowed by Scandinavian committees in recognition of cultural and scientific advances. The will of the Swedish chemist Alfred Nobel, the inventor of dynamite, established the prizes in 1895...
by his mentor August Krogh
August Krogh
Schack August Steenberg Krogh FRS was a Danish professor of Romani background at the department of zoophysiology at the University of Copenhagen from 1916-1945...
, the 1920 Nobel Laureate winner for physiology and medicine.
Knisely's positions included a term as chairman of the Department of Anatomy at the Medical College of South Carolina (1948–1974).
In 1983 The International Society on Oxygen Transport to Tissue
International Society on Oxygen Transport to Tissue
The International Society on Oxygen Transport to Tissue is an interdisciplinary society of approximately 300 members that represents essentially every major tissue oxygen research laboratory in the world...
established the Melvin H. Knisely Award to honor Knisely’s accomplishments in the field of the transport of oxygen and other metabolites
Metabolomics
Metabolomics is the scientific study of chemical processes involving metabolites. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles...
and anabolites
Anabolism
Anabolism is the set of metabolic pathways that construct molecules from smaller units. These reactions require energy. One way of categorizing metabolic processes, whether at the cellular, organ or organism level is as 'anabolic' or as 'catabolic', which is the opposite...
in the human body.