Medullary breast carcinoma
Encyclopedia
Medullary breast carcinoma is a rare type of breast cancer
that often can be treated successfully. It is marked by lymphocytes (a type of white blood cell
) in and around the tumor
that can be seen when viewed under a microscope.
This is the only breast cancer associated with a loss of function mutation in BRCA1, and thus the only form associated with a hereditary mutation. HER2/NEU over-expression is associated with sporadic breast cancer.
This is one of five important types of epithelial breast cancer: ductal, lobular, medullary, colloid, and tubular.
This is the only breast cancer associated with a loss of function mutation in BRCA1, and thus the only form associated with a hereditary mutation. HER2/NEU over-expression is associated with sporadic breast cancer.
Breast cancer
Breast cancer is cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk. Cancers originating from ducts are known as ductal carcinomas; those originating from lobules are known as lobular carcinomas...
that often can be treated successfully. It is marked by lymphocytes (a type of white blood cell
White blood cell
White blood cells, or leukocytes , are cells of the immune system involved in defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a...
) in and around the tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...
that can be seen when viewed under a microscope.
This is the only breast cancer associated with a loss of function mutation in BRCA1, and thus the only form associated with a hereditary mutation. HER2/NEU over-expression is associated with sporadic breast cancer.
This is one of five important types of epithelial breast cancer: ductal, lobular, medullary, colloid, and tubular.
External links
- Medullary breast carcinoma entry in the public domain NCI Dictionary of Cancer Terms
This is the only breast cancer associated with a loss of function mutation in BRCA1, and thus the only form associated with a hereditary mutation. HER2/NEU over-expression is associated with sporadic breast cancer.