Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

Also called nordihydroguaiaretic acid, NDGA, and actinex.

Mechanism

Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.

It is a lipoxygenase inhibitor

Lipoxygenase inhibitor

A Lipoxygenase inhibitor is a drug that slows down or stops the action of the lipoxygenase enzyme. The term is almost always used to describe an inhibitor of the arachidonate 5-lipoxygenase enzyme, which transforms EFAs into leukotrienes.Examples include:...

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External links

• MedlinePlus Drug Information
• Actinex entry in the public domain NCI Cancer Dictionary