MIS12
Encyclopedia
Protein MIS12 homolog is a protein
that in humans is encoded by the MIS12 gene
.
with NSL1
, ZWINT
, CASC5
, Polyamine-modulated factor 1
, NDC80
, DSN1
and CBX5
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the MIS12 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
MIS12 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with NSL1
NSL1
Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene.-Interactions:NSL1 has been shown to interact with MIS12 and DSN1.-Further reading:...
, ZWINT
ZWINT
ZW10 interactor is a protein that in humans is encoded by the ZWINT gene.- Function :Zwint-1 is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores...
, CASC5
CASC5
Protein CASC5 is a protein that in humans is encoded by the CASC5 gene.-Further reading:...
, Polyamine-modulated factor 1
Polyamine-modulated factor 1
Polyamine-modulated factor 1 is a protein that in humans is encoded by the PMF1 gene.-Interactions:Polyamine-modulated factor 1 has been shown to interact with MIS12.-Further reading:...
, NDC80
NDC80
Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene.-Interactions:NDC80 has been shown to interact with MIS12, NEK2 and PSMC2.-Further reading:...
, DSN1
DSN1
DSN1, MIND kinetochore complex component, homolog , also known as DSN1 or MIS13, is a protein which in humans encoded by the DSN1 gene.-Function:...
and CBX5
CBX5 (gene)
Chromobox protein homolog 5 is a protein that in humans is encoded by the CBX5 gene.-Interactions:CBX5 has been shown to interact with HDAC9, Ku70, MIS12, Lamin B receptor, MBD1, TAF4, Histone deacetylase 5, TRIM28, HDAC4, CBX3, SMARCA4, DNMT3B, CHAF1A, CBX1 and SUV39H1....
.