MED16
Encyclopedia
Mediator of RNA polymerase II transcription subunit 16 is an enzyme
that in humans is encoded by the MED16 gene
.
with Thyroid hormone receptor alpha
, Estrogen receptor alpha
and Cyclin-dependent kinase 8
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the MED16 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
MED16 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Thyroid hormone receptor alpha
Thyroid hormone receptor alpha
Thyroid hormone receptor alpha also known as nuclear receptor subfamily 1, group A, member 1 , is a nuclear receptor protein that in humans is encoded by the THRA gene.- Function :...
, Estrogen receptor alpha
Estrogen receptor alpha
Estrogen receptor alpha , also known as NR3A1 , is a nuclear receptor that is activated by the sex hormone estrogen...
and Cyclin-dependent kinase 8
Cyclin-dependent kinase 8
Cell division protein kinase 8 is an enzyme that in humans is encoded by the CDK8 gene.-Interactions:Cyclin-dependent kinase 8 has been shown to interact with MED16, MED26, MED17, MED14, CREB binding protein, MED1, MED6, MED24, CCNC, POLR2A, MED21, SMARCB1, MED12 and CRSP3....
.