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Lysidine (chemical)
Encyclopedia
Lysidine is an imidazoline
derivative. This compound can be an intermediate in the synthesis of metronidazole
; it may be prepared by reacting ethylenediamine with acetic acid
to give the diamide, followed by treatment with lime. Raney nickel
dehydrogenates it to 2-methylimidazole.
Imidazoline
Imidazoline is a nitrogen-containing heterocycle with formula C3H6N2, derived from imidazole. The ring contains an imine bond, and the carbons at the 4 and 5 positions are singly bonded, rather than doubly bonded for the case of imidazole...
derivative. This compound can be an intermediate in the synthesis of metronidazole
Metronidazole
Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal....
; it may be prepared by reacting ethylenediamine with acetic acid
Acetic acid
Acetic acid is an organic compound with the chemical formula CH3CO2H . It is a colourless liquid that when undiluted is also called glacial acetic acid. Acetic acid is the main component of vinegar , and has a distinctive sour taste and pungent smell...
to give the diamide, followed by treatment with lime. Raney nickel
Raney nickel
Raney nickel is a solid catalyst composed of fine grains of a nickel-aluminium alloy, used in many industrial processes. It was developed in 1926 by American]] engineer Murray Raney as an alternative catalyst for the hydrogenation of vegetable oils in industrial processes...
dehydrogenates it to 2-methylimidazole.