Lymphomatoid granulomatosis
Encyclopedia
Lymphomatoid granulomatosis is a neoplastic disease.
It is a lymphoproliferative disorder (lymphomatoid means lymphoma-like). The word granulomatosis denotes one of its microscopic character, polymorphic lymphoid infiltrates and focal necrosis
within it.
While most commonly found in older patients, in 2008 the youngest patient ever (13) was diagnosed with this cancer.
It usually involves lung, skin, and central nervous system.
It was first characterized in 1972.
.
There currently is a protocol being run by Dr. Wyndham H. Wilson at the NIH. The experimental treatment involves the use of interferon
s.
It is a lymphoproliferative disorder (lymphomatoid means lymphoma-like). The word granulomatosis denotes one of its microscopic character, polymorphic lymphoid infiltrates and focal necrosis
Necrosis
Necrosis is the premature death of cells in living tissue. Necrosis is caused by factors external to the cell or tissue, such as infection, toxins, or trauma. This is in contrast to apoptosis, which is a naturally occurring cause of cellular death...
within it.
While most commonly found in older patients, in 2008 the youngest patient ever (13) was diagnosed with this cancer.
It usually involves lung, skin, and central nervous system.
It was first characterized in 1972.
Prognosis
There is no known cure. It is resistant to ordinary chemotherapyChemotherapy
Chemotherapy is the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen....
.
There currently is a protocol being run by Dr. Wyndham H. Wilson at the NIH. The experimental treatment involves the use of interferon
Interferon
Interferons are proteins made and released by host cells in response to the presence of pathogens—such as viruses, bacteria, or parasites—or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.IFNs belong to...
s.